Lecture 7

Question 1

What is process of bone growth?

Answer 1

Bones begin as a catalogue model and then

transformed into bone in the process called ossification.

Question 2

What are the different parts of a growing bone?

Answer 2

Primary ossification centre:
> Diaphysis

Secondary ossification centre:
> Epiphysis

Growth plate:
> between diaphysis and epiphysis
called the epiphyseal growth plate

Question 3

Bone pathology

Answer 3

Imbalance of Osteoblasts and Osteoclasts activity.
e.g. Osteoporosis the Osteoclasts overtake the Osteoblasts, results in thin & porous compact bone, loss of volume in cancellous bone, compression fractures in vertebrae.

Question 4

What are the causes of osteoporosis?

Answer 4

Age - loss of oestrogen 
Life Factors 
> lack of exercise
> nutrition
> peak bone mass - bone as a bank

Question 5

What are the stages of a fracture?

Answer 5

Stage One
> Haematoma
> Capillaries
> Phagocytes

Stage Two
> Fibroblasts 
> Chondroblasts 
> Chondro = cartialge 
> Fibrocartilaginous callus 

Stage Three
> Bone callus
> Osteoblasts

Stage Four
> Remodelling