Lecture 7 Flashcards
most important method of prophylactic method
immunoprophylaxis
goal of immunisation
induce immunity
vaccine definition
suspension of live (usually attenuated) or inactivated microorganism to induce immunity and prevent infectious diseases
vaccination definition
physical act of administering any vaccine or toxoid
immunisation definition
process of being made immune or resistant to an infectious disease
MDA
horse pig cow dog and cat’s MDA cannot pass through the placenta
so they need to ingest colostrum within 24 hrs after birth and the colostrum decreases oveer tie
it’s absorbed in SI, goes to lymph then circulation and then provides immunity
must ingest during 1st 2 hours of life; 6 hours after birth they’re detectable
passive immunity
- transfer of antibody produced by one animal to another
- natural (colostral0
- artificial (passive immunisation0
- passive immunisation = transfer of antibodies to an unprotected individual for the prevention or treatment of disease
adverse reaction = hypersesntiivty
protection = short lasting
types of vaccine
infectious
- attenuated
- heterologous
- recombinant
non-infectious
- whole pathogen
- subunit
- conjugated
- toxoid
- DNA/RNA
type 1 hypersensitivity
- IgE
immediate hypersensitivity
dogs present with skin and general circulation signs
cats have gastrointestinal and respiratory signs
type 2 hypersensitivity
production of IgG and IgM antibodies binding to specific cell surface antigens and producing cytotoxicity
type 3 hypersesntivity
develop from acute inflammation triggered by presence of immune complexes in tissues
type 4 hypersensitivity
involves cell-mediated immune responses
take more than 12 hours to develop