Lecture 65 + 66 - Zoonoses and Ricketsia

Question 1

Brucella is a “_____” disease, in that most people who are infected in the US have recently visited areas where animals are not vaccinated, and they have consumed dairy products.

Answer 1

“Traveler’s” disease

Question 2

Listeria can cross the _______, so pregnant women are discouraged from eating soft cheeses and unwashed produce.

Answer 2

Placenta

Question 3

Unlike Ricketsia which infect ______ cells, Ehrlichia and Anaplasma infect WBCs. Which do they infect, respectively?

They have a biphasic lifestyle with an EB and RB form. Which other organism is this like?

Answer 3

Endothelial cells

Ehrilichia –> Monocytes (Human Monocyte Ehrlichiosis - HME)

Anaplasma –> Granulocytes (Human Granulocyte Anaplasmosis - HGA)

This is just like Chlamydia spp.

Question 4

Q (Query) Fever is caused by ______ burnetti. Those at high risk are farm workers or slaughterhouse workers. Dried _______ materials are a rich source of infectious particles. It produces high fever _______-like pneumonia, and ______ in about 50% of cases. Keep in mind it is very pathogenic, and is ____-stable –> can be transmitted via droplets and dust particles.

Answer 4

Coxiella burnetti (obligate intracellular)

Placental

Mycoplasma-like pneumonia

Hepatitis

Air-stable