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PHRM 847 > Lecture 6 - Online Resources Pt2 > Flashcards

Lecture 6 - Online Resources Pt2 Flashcards

1
Q

What is the best website for meds + genetic interactions prescribing info?

A

Pharmgkb

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2
Q

What does the pharmgkb prescribing info tell us?

A

Explains how to adjust tx of certain meds based on genetic info, includes clinical guidelines, drug labels, and Rx studies

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3
Q

What source on pharmgkb is the genetic info guideline in the US?

A

CPIP

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4
Q

What test is done to figure out a pt’s genetic makeup?

A

Genetic testing

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5
Q

You order a DNA test for your pt to sequence all possible alleles in all exons of CYP2C19 genes. After sequencing, NO KNOWN MUTANT allele was identified (this is why it was called as 1/1. However, a NOVEL MUTATION (heterozygous) in CYP2C19 exon 3 was ID’d. This allele has never been described in literature. What would you do w this finding?

A

More info is needed to evaluate its clinical consequence

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PHRM 847 (12 decks)

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