Lecture 1 - Intro to pgx Flashcards
1
Q
What is actionable signature?
A
Information used to make treatment decision
2
Q
Genetic markers can distinguish pts:
A
- who are most likely to respond to a drug
- who are most likely to develop SEs
- who should not take the drug
- the best dose to be taken
3
Q
How many pharmacogenomic drug labels have the FDA approved as of 2018?
A
150
4
Q
How many pharmacogenomic entries were there in 2020 and 2023?
A
385 and 517
5
Q
What is PK?
A
- What the body does to the drug
- ADME
6
Q
What is pharmacodynamics?
A
- What the drug does to the body
- Receptor, target, signaling, enzymes
7
Q
What is the pharmacist’s role in pgx?
A
- Recommending or scheduling pgx testing
- Designing pt specific drug and dosage regimen based on pt’s pgx profile
- Educating
- Communicating pgx specific drug therapy recommendations
8
Q
List the competency domain and pharmacist specific knowledge.
A
9
Q
List the competencies of genetics and disease.
A
10
Q
List the competencies of pharmacogenetics and pharmacogenomics.
A
11
Q
List the competencies of ethical, legal, and social implications of pgx.
A
