Lecture 6 - Model organisms in research

Question 1

Median lifespan of model organisms

Answer 1

Yeast - 23 generations
C. elegans - 2-3 weeks
Fruit fly - 2-2.5 months
Killifish - 4-6 months
Mouse - 2 years
Zebrafish - 3.5 years

Question 2

The turquoise killifish genome was sequenced in

Answer 2

2015

Question 3

Turquoise killifish scientific name

Answer 3

Nothobranchius furzeri (N. furzeri)

Question 4

2 advantages of N. furzeri

Answer 4

1. Short lifetime with rapid development
2. A diapause state (kind of like hibernation of the embryo)

Question 5

N. furzeri have what two distinct phases?

Answer 5

1. A fast-growing phase in the rainy season
2. A suspended phase in the dry season

Question 6

The Animal Study Protocol, or the IACUC (Institutional Animal Care and Use Committee) is

Answer 6

a detailed description of the proposed use of animals prepared by the researcher for IACUC review and approval