Lecture 6 Epithelial Glands Flashcards
2 Types of Glandular Epithelium
- Exocrine
2. Endocrine
Exocrine glands
Epithelial outgrowths into underlying connective tissue that retain connection to the overlying epithelium in form of one or more ducts
Secrete product through a duct and onto epithelium or into a duct lined in epithelium
Endocrine glands
Have lost connection, they are ductless. Had one when forming, their product is systemic
2 Types of Endocrine
- Paracrine - affects neighbors
2. Autocrine - self affected
Paracrine
Secretion affects neighboring cells
Autocrine
Secretion affects self
3 Ways to classify glands
- Number of cells
- Absence or presence of ductal dranching
- Shape of secretory portion
Unicellular
Columnar epithelium - one cell comprises the gland
Ex. Goblet cell - secretes mucous, look like mini wine glasses, look clear blue, no duct
Multicellular
NOT unicellular
gland made of multiple cells
2 ways to name gland based on number of cells
Unicellular
Multicellular
Classification of glands based on absence or presence of ductal branching
- Simple
2. Compound
Classification of glands based on shape of secretory portion
- Tubular
- Acinar - aka Alveolar - flask shaped
- Tubulo-alveolar (-acinar)
2 Types of multicellular glands
- Simple excretory duct
(tubular, coiled, tubular branched, acinar/alveolar) - Compound (branched) excretory duct
(branched tubular, branched acinar, branched tubulo-acinar)
Organization of Compound (branched) excretory duct:
Capsule
Septa or trabeculae (divide gland into lobules and lobes)
Lobe
Lobule
Capsule
Connective tissue sheath that surronds the compound excretory duct
Septa
aka Trabeculae
Extensions of capsule that extend into the gland
Divide gland into lobules and lobes
Lobe
Larger than lobule
Lobule
Little lobe
Smallest anatomical part of gland
3 Types Lobule
- Intralobular duct
- Striated/intercalated duct - microscopically they have invaginations on surface domain for increased surface domain
- Acinus
- Musous
- Serous
- Serous-mucous (mixed)
Intralobular duct
Intra = within
Within a lobule
Striated/intercalated duct
Intralobular duct
Microscopically they have invaginations on surface domain for increased surface area
Often have high E job
Mechanism of secretion (classification of glands) 3 ways to classify
- Merocrine (eccrine) - seous - these two go together, cells remain intact. many of these in body
- Apocrine - secretory product is thicker, most of cell intact and can be repaired Ex. Mammary and sweat glands
- Holocrine - secretion is too thick to get out of cell and it bursts. Ex. sebum
Compound Gland Acinus
Secretory part of the gland
Basement membrane (sits on this)
Myoepithelial cells - these surround the cells on the outside. Spindle shaped, derived from epithelium
5 Structures of Compound Gland
- Intralobular
- Interlobular
- Intralobular
- Lobar duct
- Main duct