Lecture 6 Flashcards
Mammalian sperm must undergo _____ in female reproductive tract
capacitation
Capacitation can be done in vitro with
albumin, bicarbonate and calcium
Capacitation allows for
a loss of cholesterol from sperm membrane. =
makes them more permeable and increases motility
Mammalian Egg- has a layer of follicle cells called
the cumulus
mammalian egg- inside the cumulus is an extracellular coat
zona pellucida, rich on hyaluronic acid
gel-like cytoplasm in egg
cortex
inner most layer of the cumulus is called the
corona radiata
Blocks to polyspermy- cortical granule reaction occurs fusing with
egg cell membrane
cortical granule serine protease is released
this removes binding sites for sperm
release of mucopolysaccharides changes osmotic gradient
water rushes into space, expanding vitalize membrane. This is now called the fertilization membrane
blocks to polyspermy- peroxidase enzyme released
hardens fertilization membrane
Block to polyspermy- Hyalin released forms
coating around egg to support blastomeres.
The ovaries produce ______ and deposit them in the the ______
oocytes, oviduct
The _______ sweep the eggs in tote oviduct where they travel to the uterus
Fimbriae
Unlike many other organisms the egg in mammals undergoes ______ cleavage.
asynchronous cleavage, this allows for a frequent odd number of cells