Lecture 5 theme B Flashcards
1
Q
What is the structural effect of ANG2 on the heart?
A
Hearts with intracardiac ANG2 are often hypertrophic and as a result, too much of this hormone is harmful.
2
Q
How does ANG2 production affect the heart?
A
chronic overexpression of ANG2 results in smaller pump function and slower heart rate.
Acute expression results in the opposite effect.
3
Q
What are the effects of ANP on the heart?
A
negative inotropic agent (decreases heart contraction strength)
Promotes water and sodium excretion to reduce circulating volume
