Lecture 5: Horse Hepatic Dysfunction

Question 1

Acute Hepatic Necrosis/Theiler’s Disease

Answer 1

associated with receiving EQUINE BIOLOGICS

Question 2

When is Theiler’s Disease most commonly seen?

Answer 2

the Fall

Question 3

Tyzzer’s Disease

Answer 3

YOUNG FOAL 1-2 months of age, caused by Clostridium Piliformis

Question 4

What is Tyzzer’s Disease caused by?

Answer 4

C. piliformis

Question 5

How do you treat Tyzzer’s and what’s Px?

Answer 5

Penicillin and Poor

Question 6

Equine Neonatal Herpes Virus?

Answer 6

Dies in FIRST WEEK of life

Question 7

What antitoxin is associated with Theiler’s Disease?

Answer 7

Equine biologic for TETANUS antitoxin

Question 8

Toxic Hepatitis

Answer 8

Liver MEGALOCYTOSIS
caused by Pyrrolizidine Alkaloids
Crotalaria, Senecio, Amsinkia

Question 9

What’s the halmark cytology of Toxic Hepatitis?

Answer 9

Liver biopsy showing MEGALOCYTOSIS, cell death and fibrosis

Question 10

What is toxic hepatitis in horses caused by?

Answer 10

Pyrrolizidine Alkaloids: Amskinkia, Crotalaria, Senecio

Question 11

What does Cholelithiasis look like in horses?

Answer 11

recurring colic, hepatic encephalopathy, photosensitization, jaundice

Question 12

How do you dx cholelithiasis?

Answer 12

Ultrasound

Question 13

Hyperlipemia

Answer 13

Fatty Liver

smaller word smaller horses: Miniature Horses, Small Pony breeds and draft horses and donkeys

Question 14

What is the triglyceride threshold for treatment of hyperlipemia? What is normal?

Answer 14

> 100mg/dL for treatment. 11-57mg/dL

Question 15

Hyperlipidemia

Answer 15

Old Fat Horse anorexic; less severe than hyperlipemia