Lecture 5 - Big Data

Question 1

Why cant we truly unravel the jigsaw puzzle?

Answer 1

Neuro-Bio-Psychosocial Jigsaw

*Focus on groups instead of single individuals
*Small studies and traditional analytics
*Research harmonization is lacking
*Low sociodemographic diversity
*Mono-disciplinary research
*Limited “team science

Question 2

What are the 3 elements in the psyhology paradigm shift?

Answer 2

I.Move from group to
individual-level inferences
II.Employ
Big Data & Modern
Statistics
III.Enhance interdisciplinarily
“Team Science”

Question 3

What is the problem with Group Level Analysis?

Answer 3

Classic Case-Control studies overlook Heterogeneity.

• Sensitivity / specificity / validity issues
• Small & Difficult to replicate effects
• Unable to predict diagnosis, course and treatment response

Question 4

What is Big Data?

Answer 4

“Big Data” refers to data that is
so large, fast or complex
that it’s difficult or impossible to process using traditional methods

Question 5

What are the benefits of Team Science?

Answer 5

*More data/resources/brain power
*Better expertise & multi-disciplinary
*Oversight and control on each other
*Correction of malpractice and disintegrity
*Harmonization of methods across the field

Question 6

What is the Scientific, Clinical and Societal Impact

Answer 6

1. Personaized Diagnostics and Prognostics
2. Early detection for tailored prevention and care
3. Reduced burden on family and society.