Lecture 5 Flashcards

1
Q

What is nociception

A

nociception = pain perception and it is different from pain experience

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2
Q

What is pain perception sensitive to?

A

pain perception is very sensitive to environmen

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3
Q

UNDERSTAND THE DIAGRAM ON CHAPTER 5 SLIDE 4

A
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4
Q

Where does the exchange between mom and baby happen for oxygen, waste products, and nutrients?

A

We mentioned that there is a membrane in the intravilli space where the exchange actually happens. This is where oxygen, Co2 etx get transferred. When you’re studying for an exam and are looking at a diagram, know the concepts of the words she talks about in the slides.

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5
Q

What does pain lead to the release of? How does this work to regulate contractions with oxytocin? When is this mostly true?

A

Pain leads to the release of
* stress-related hormones and neurotransmitters
* endogenous opioids (when pain reaches a relatively high level (happens at different time for different people (pain tolerance)) it also releases endogenous opiods which try to facilitate pain relief. )

What these hormones do is interact with oxytocin which is the hormone that leads to uterine contractions. As we said contractions swithc from neuronal to hormonal control. Because pain is related to these other hormones, they will try to reduce the oxytocin, but we need oxytocin to contract. These stress related hormones reduce the level of contraction in this way. This is mostly true in stage 1 of labour. In stage, 2 stress hormones are different. Stress hormones in stage 1 (dialation) leads to the slowing down of labour and therefore slowing down contractions.

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6
Q

How can pain reduce the strength and duration of labour contractions?

A

Pain can suppress the release of oxytocin (the hormone that causes labour contractions). In this way, pain can serve to reduce the strength and duration of contractions, especially during stage 1 of labour.

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7
Q

When can contractions actually injur the mother? Why?

A

in rare occaisions really strong contractiosn can hurt the mother because the tissues of the mother aren’t getting supplied with oxygen either.

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8
Q

Does pain serve to prevent injury to the mom and baby during labour? How? (2 ways)

How might this be a problem when thinking about epidurals?

A

Pain during labour as the body’s way of preventing injury to mom and baby

The reason why labour pain can eb a way of preventing injury is because pain leads to the release of a number of substances in the body. The higher the painful sensation the more of these will be released. its the body’s way of coping with painful sensations.

The reason it can prevent injury is that it reduces some of the oxygen deprivation (slowing down labour through the release of these hormones decreases some of the oxygen deprivation). Every labour conraction leads to the slowing down or shutting down of the exchange of nutrients, oxygen etc hat needs to go to the baby. This is the natural pain process and it results in prevention of injury because it naturally regulates the strengths of contractions because if the body sees it as pain then the stress hormones will be released. In the case of epidurals, they remove sensation of the organs (the systemic one), the opiods coming from the epidural slow down labour and sometimes it stops, and that slowing down and stoping leads to the introduction of pitocin. They essentially shift control of the labour from the body to external chemicals.

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9
Q

why might a soldier with an open womb may be doing things without realizing the pain?

A

when pain reaches a relatively high level (happens at different time for different people (pain tolerance)) it also releases endogenous opiods which try to facilitate pain relief.

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10
Q

What hormone causes labour contractions?

A

oxytocin

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11
Q

Is there a difference between pain, nociception, and harm?

A

we are trying to distinguish and relate the concept of pain, nociception and harm . In our common culture these things tend to be mixed up but something that is really important is that pain is not always equated with harm.

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12
Q

Is pain more than nociception?

A

yes

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13
Q

What is nociception?

A

The encoding and processing of harmful stimuli in the nervous system, leading to a body’s ability to sense potential harm

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14
Q

How are nociception and pain different?

A

Nociception is not the same as pain
* Nociception: the sensory process that produces the
nerve signals that trigger pain
* Pain: a subjective experience (aching sensation)

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15
Q

What is a good exmaple of how pain and nociception are different?

A

example is phantom pain with people who have had an amputated leg or arm. The nociception fibres do not exist in this case but pain does exist. nociception is the lower level of processing of sensation and pain leads to the higher level of processing.

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16
Q

What does lower level processing refer to? Is nociception lower of higher level processing? is pain lower or higher?

A

Usually lower level processing refers to levels that come towards the periphery of the body and the higher ones go towards the brain

nociception is the lower level of processing of sensation and pain leads to the higher level of processing.

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17
Q

how is nociception a specific part of our pain perception mechanism?

A

nociception is a very specific part of our perception mechanism that is dedicated to potentially harmful stimuli, the harm is not necessarily actual harm, you can feel pain to avoid ignoring a potential danger.

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18
Q

What is nociception usually identified with? How does this differ from pain?

A

nociception is identified with noxious sensory input (any changes to the body that could cause potential harm). Pain is actually the private experience that can be informed by the noxious sensory input, or it can inform the noxious sensory input.

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19
Q

What is an exmaple of how judgments can influence the experience of pain?

A

Ex: if you believe the bible saying that labour pain is punishment from eve then this expectation will change your experience of pain.

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20
Q

KNOW THE DIAGRAM ON LECTURE 5 SLIDE 9

A
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21
Q

What is the McGill pain scale? What is problematic about it?

A

This is a pain scale used in a lot of medical and research. It only refers to the sensory aspect of pain but it is problematic because it doesn’t consider this other framework. This is an exampel of how if you see results coming from this scale, you should take it with a grain of salt.

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22
Q

How did the McGill painscale classify chilbirth? What does he ignore?

A

if you browse the internet and look up pain and childbirth you will come across one of these. This is one of the images that you see that will give you an idea of how much labour hurts and it comes from the mcgill pain scale. he would ask people with tooth aches, etc to rate their pain and then he compared them and this then became a visual fixture to indicate how much labour hurts. The big message was that the only other thing that hurts more than childbirth is having your finger cut off. Whats being ignored the nuances of pain. not paying attention to conceptual, social and other frameworks aroudn this

23
Q

KNOW THE DIAGRAM ON LECTURE 5 SLIDE 11 (mcgill pain scale)

A
24
Q

What does nulli paras mean?

A

Nulli paras means have never had a baby. These women have never parted with a baby. (miscarriages are classified as nullipara)

25
Q

What does multiparas mean?

A

Multiparas is people who have had a baby before.

26
Q

Why does research often make a classification/distinction of multiparas vs nuliparas?

A

the reason they do these classifications is because the uterus is trained in the first birth and it should be a little easier the second time

27
Q

What is the issue with scales that tell you how much child birth hurts based off of subjective reports?

A

Subjective reports are very variable. This graph tells you how much childbirth hurts but it ignores that there are a lot of individual differences. Some women experience severe pain. Some women experience low or no pain, and some people experience moderate to sever pain. So what can these graphs really tell you about your potential experience? Also this scale disregards the one off cases like the orgasmic birth.

we should take mean scores with lots of suspiciaon

28
Q

What are alternative birth centers?

A

Alternative birth centers are something in between. They are not your home but they are also not a hospital. Its made to feel more like a home and they don’t have the ability to administer things like epidurals etc.

29
Q

What were the results of the denmark study that was researching whether doing hospital birth or birthing centers influenced pain levels?

A

this study examined home vs hosp birth in more detail. They asked people to compare different sensations of pain to the sensation of giving burth (didn’t focus on just the sensation of pain). Based on the pairwise ratings they constructed a scale. They used multidimensional scaling. It basically infers a person’s conceptual space. If we showed you pairs of foods you can infer the person’s conceptual space because at the end the scaling will see consistency between the preferences and you can tell people what their preferences are. We don’t need to know this I just wanted to know.

People who had home birth’s (149 women) ranked childbirth at a 3.5 (below broken bone)

People who had hospital births (102 women) ranked childbirth at a 12.1 approx., just above kidney stones

This study actually also asked the partners of women giving birth to rate their perception of how much their partner was in pain. Results were less varied but still showed higher percpetion of pain from the partners in hospital cases. This shows that the setting is more important for the first hand experience of pain than for those watchign them

30
Q

Is the experience of pain context dependent? What do contexts include?

A

yes.

The context includes
* our own mind and the conceptual framework with which we interpret the experience
* the people around us, with their own conceptual frameworks that determine what these people say to us and how they view us

31
Q

Are we measuring nociception or pain when we ask people to tell us about their experience?

A

We are going through experience of pain, not nociception

32
Q

How does the definition of nociception relate to sensory fibres?

A

nociception is sensory fibres carrying sensation

33
Q

How does the pregnant uterus detect nociception, how does the non-pregnant uterus detect nociception? Which is stronger?

A

nociception during the end of pregnancy is stronger from the sensory fibres would detect mainly chemical changes but the non pregnant uterus can also experience nociception from the mechanical process of cramping etc.

34
Q

Does a sensation have to be felt to a specific degree to trigger nociception?

A

a sensation has to be felt at a certain level to trigger nociception. When the sensation reaches an intensity of a certian severe stage that is when nociception is triggered.

35
Q

How can environments vary? AKA what are some things that may influence the differences in experience between home and hospital? (6 things)

A

Degree of
* strangeness
* noise
* lighting
* temperature
* restrictiveness in terms of space
* restrictiveness in terms of movement

36
Q

What does supine mean?

A

Supine means lying on your back

37
Q

Is standing up vs supine part of a context?

A

yes.

38
Q

What is the difference in experience from standing up vs supine birth?

A
  • Standing up is more comfortable than lying on one’s back (19/20 women)
  • Standing up is less painful than lying on one’s back (15/20 women)
39
Q

Do birthing pools make a difference compared to ‘dry land’ ? Why>

A
  • Being in warm water tends to reduce pain significantly

with smooth muscles, warmth tends to reduce pain signfiicantly

40
Q

Is there a right time to get in the birthing pool?

A

lots of people wonder when is the right time to get into the birthing pool? warmth relaxes the smooth muscles and also reduces the contractility of the smooth muscle. your labour could stop completely if you go in too soon.

41
Q

What 2 areas can nociceptive input be divided into?

A

visceral and non-visceral (somatic)

42
Q

What is visceral nociception? Where does it come from? What is it carried by?

A

From internal organs of the body, e.g.:
* Liver
* Gut
* Stomach
* Bladder
* Blood vessels
Carried largely by C fibres

43
Q

What is non-visceral (somatic) nociception? What is it carried by?

A

From body parts that are not internal organs
* Bones
* Ligaments
* Skeletal muscles * Skin
Carried largely by A-delta fibres

44
Q

What is fibre another word for?

A

neurons

45
Q

What is noxious sensory input carried by?

A
  • Carried by A-delta and C fibres ascending nociceptive fibres
46
Q

Which fibres are considered evolutionarily older? C-fibres or A-delta fibres?

A

new: A-delta

Old: C-fibres

47
Q

are A-delta fibres related to slow pain or fast pain?

A

fast pain

48
Q

are Cfibres related to slow pain or fast pain?

A

slow

49
Q

What kind of pain do A-delta fibres carry?

A

mechanical and thermal

50
Q

What kind of pain do C fibres carry?

A

mechanical, thermal, and chemical

51
Q

What is the biggest different between A-Delta and C fibres?

A

A-delta fibres are myelinated (This contributes to sharp pain like burnign yourself etc.) and c fibres are not (The slow pain is from the visceral organs its like a dull slow aching that annoys you. This is because they are carried by these slow fibres that don’t have insulation or myelin aroudn them )

52
Q

How do A-delta and C fibres differ in diameter?

A

A delta = 1-5 micrometers
C = 0.2-1.5 micrometers

53
Q

How do A-delta and C fibres differ in conduction speed?

A

A delta = 5-40 m/s
C = 0.5- 2