Lecture 4 - Mydriatics Cycloplegics

Question 1

Hormones including dopamine, epinephrine and norepinephrine; produced from tyrosine in postganglionic fibers of the autonomic nervous system and the adrenal medulla

Answer 1

Catecholamines

Question 2

Catechol-O-methy transferase; an enzyme of catecholamine metabolism

Answer 2

COMT

Question 3

Monoamine oxidase; an enzyme of catecholamine metabolism

Answer 3

MAO

Question 4

Pupillary contraction

Answer 4

miosis

Question 5

Pupillary dilation

Answer 5

mydriasis

Question 6

Paralysis of the ciliary body musculature responsible for accommodation.

Answer 6

cycloplegia

Question 7

Which Ig in the bloodstream reacts with the antigen leading to histamine release, bronchoconstriction, vasodilation and swelling?

Answer 7

IgE

Question 8

Fight and Flight is regulated by the __________ or ____________ branch of the ANS.

Answer 8

Sympathetic/adrenergic; autonomic nervous system

Question 9

Rest and Digest is regulated by the ___________ or ____________ branch of the autonomic nervous system.

Answer 9

Parasympathetic / cholinergic

Question 10

Epinephrine and Norepinephrine are part of the ________ ANS NTs.

Answer 10

sympathetic

Question 11

Presynaptic +a2 receptor stimulates/inhibits signal propagation

Answer 11

inhibits

Question 12

Stimulation of a1: vasoconstriction/vasodilation

Answer 12

vasoconstriction

Question 13

Stimulation of b2: vasoconstriction/vasodilation

Answer 13

vasodilation

Question 14

Stimulation of b2 in lungs? dilation or constriction?

Answer 14

bronchodilation

Question 15

Stimulation of b1 in heart: increase/decrease contractility and conduction.

Answer 15

increase contractility and conduction

Question 16

In the liver stimulation of b2 causes?

Answer 16

glucogenolysis; break down of glycogen and dumping into the bloodstream

think of it facilitating fight/flight.

Question 17

In the pancreas stimulation of b2 causes increase/decrease in insulin release.

Answer 17

increase in insulin release

Question 18

In the pancreas stimulation of a2 causes increase/decrease in insulin release.

Answer 18

decrease in insulin release

Question 19

In the iris, stimulation of a1 causes _______.

Answer 19

mydriasis

Question 20

In the ciliary body stimulation of b2 causes constriction/relaxation and increase/decrease in aqueous production.

Answer 20

Relaxation and increase in aqueous production

Question 21

In the ciliary body stimulation of b2 or a2 causes increase/decrease in aqueous production.

Answer 21

decrease aqueous production

Question 22

What does a1 receptor respond to?

Answer 22

NE > E

Question 23

What does a2 receptor respond to?

Answer 23

E >/equal NE

Question 24

What does b1 receptor respond to?

Answer 24

E = NE

Question 25

What does b2 receptor respond to?

Answer 25

E

Question 26

Catecholamines comes from what amino acid?

Answer 26

tyrosine

Question 27

What is responsible for the liberation of DA (dopamine) and NE from the nerves vesicles?

Answer 27

Ca+2

Question 28

In the ocular system an increase in IOP, risk in angle closure, and allergic reaction are adverse effects of what?

Answer 28

anticholinergics

Question 29

The adverse effects of anticholinergics systematically are the ABCCDSS

Answer 29

Anorexia, Blur, Constipation & Confusion, Dryness, Sedation & Stasis of urine.

Question 30

In the CNS (medulla) you get a decrease in Parkinson tremor and HR by this cycloplegic drug.

Answer 30

Anticholinergics

Question 31

Which cycloplegic would have give with these indications? | mydriasis, dose-dependent cycloplegia, less pigment-sensitivity than cyclopentolate, homatropine and atropine,

Answer 31

tropicamide