Lecture 3 - Anaesthetics Flashcards
Lidocaine
- group?
- indications?
- onset/duration
- amide
- LA, RA, status epilepticus, ventricular arrhythmia, forced ructions, chalazion surgery
- 4-6 mins / 2/3-1 hr.
Etidocaine
- group?
- indications?
- onset/duration?
- amide
- LA
- 3-5mins / 5-10hrs
Mepivicaine
- group?
- indications?
- onset/duration?
- amide
- RA & LA
- 3-5mins/ 2-3hrs
Bupivicaine
- group?
- indications?
- onset/duration?
- amide
- LA, RA and obstetrics
- 5-10mins / 4-12hrs
Prilocaine
- group?
- indications?
- onset/duration?
- amide
2. LA topical and infiltration
Ropivacaine
- group?
- indication?
- onset/duration?
amides
LA, RA & obstetrics
Procaine
- group?
- indications
- onset/duration
- esters
- 7-8mins/ 1/2-3/4hrs
Cocaine (ester, BA) adverse effects.
System: excitement, convulsions, rapid palpitations, nausea, delirium
Ocular: desquamation, mydriasis, lid retraction (Muller’s muscle; nonvoluntary)
Myelination enhances sensitivity dependent/independent of diameters.
independent of diameter
Small/large diameter highly active nerves tend to be more sensitivity.
small diameter nerve = more sensitive
Large diameters are less sensitive and thus recover quicker/slower than small.
Quicker = less sensitive
PABAs, MABAs, and BA are all esters/amides.
esters
Tetracaine, benzocaine, procaine and benoxinate are PABA/MABA/BA?
PABA; para amino benzoic acid
Proparacaine is PABA/MABA/BA?
MABA; mono amino benzoic acid
Cocain is PABA/MABA/BA?
BA; benzoic acid