Lidocaine
Etidocaine
Mepivicaine
Bupivicaine
Prilocaine
2. LA topical and infiltration
Ropivacaine
amides
LA, RA & obstetrics
Procaine
Cocaine (ester, BA) adverse effects.
System: excitement, convulsions, rapid palpitations, nausea, delirium
Ocular: desquamation, mydriasis, lid retraction (Muller’s muscle; nonvoluntary)
Myelination enhances sensitivity dependent/independent of diameters.
independent of diameter
Small/large diameter highly active nerves tend to be more sensitivity.
small diameter nerve = more sensitive
Large diameters are less sensitive and thus recover quicker/slower than small.
Quicker = less sensitive
PABAs, MABAs, and BA are all esters/amides.
esters
Tetracaine, benzocaine, procaine and benoxinate are PABA/MABA/BA?
PABA; para amino benzoic acid
Proparacaine is PABA/MABA/BA?
MABA; mono amino benzoic acid
Cocain is PABA/MABA/BA?
BA; benzoic acid
Lidocaine, Mepivicaine, Bupivicaine, Etidocaine, Prilocaine are esters/amides.
amides
Amides are under _________ metabolism.
hepatic
Indications:
tonometry, gonio, sutures, nasolacrimal massage, ultrasound
Which anesthetic?
proparacaine / tetracaine
Indication: tonometry
Which anesthetic?
benoxinate
Indications: herpetic neuralgia (injection)
Which anesthetic?
procaine
Indications:
OTC oral, dental cough
Which anesthetic?
benzocaine
Indications:
otolaryngology
Which anesthetic?
cocaine