Lecture 3: Anatomy and Physiology of the Digestive System Part 1, and types of study designs Flashcards

1
Q

autonomic nervous system

A
  • sympathetic and parasympathetic responses
  • responsible for involuntary control
  • cardiovascular, respiratory, urinary, digestive, reproductive functions
  • adjusts electrolytes, nutrients and gases in body fluids
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2
Q

3 phases of digestion

A

cephalic, gastric and intestinal

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3
Q

How does autonomic nervous system work?

A

signals from the brain are carries to ganglia, which are then sent to peripheral target organs for either parasympathetic or sympathetic response

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4
Q

P or S?: heightened alertness

A

sympathetic response

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5
Q

P or S?: increased metabolic rate

A

sympathetic response

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6
Q

P or S?: decreased digestive and urinary functions

A

sympathetic response

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7
Q

P or S?: activation of energy reserves

A

sympathetic response

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8
Q

P or S?: increased respiration (rate and dilation of respiratory pathways)

A

sympathetic response

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9
Q

P or S?: increased heart rate and blood pressure

A

sympathetic response

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10
Q

P or S?: activation of sweat glands

A

sympathetic response

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11
Q

P or S?: decreased metabolic rate

A

parasympathetic response

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12
Q

P or S?: decreased heart rate and blood pressure

A

parasympathetic response

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13
Q

P or S?: increased secretion by salivary and digestive glands

A

parasympathetic response

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14
Q

P or S?: increased motility in the digestive tract

A

parasympathetic response

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15
Q

P or S?: increased blood flow in the digestive tract

A

parasympathetic response

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16
Q

P or S?: norepinephrine

A

sympathetic

17
Q

P or S?: acetylcholine

A

parasympathetic

18
Q

P or S?: greater divergence of reach to organs

A

sympathetic

19
Q

autonomic tone

A

the background level of activity regulating the body (ie maintaining heart rate)
-parasympathetic dominates in resting conditions, sympathetic kicks into action in an emergency

20
Q

accessory organs

A
  • digestive organs through which food is not moved, like it is moved through the digestive tract.
  • salivary glands, liver, pancreas, gall bladder
21
Q

cephalic phase

A

-starts with anticipation of food and ends with swallowing

22
Q

gastric phase

A

-the time during which food is in the stomach

23
Q

intestinal phase

A
  • starts when chyme enters the duodenum
  • controls the rate of gastric emptying
  • coordinates activities of intestinal tract, pancreas, liver and gallbladder
24
Q

saliva

A
  • made of water, glycoprotein (for viscosity), amylase, lipase
  • essential for taste perception, antibacterial
  • production lowers during sleep
25
Q

amylase

A

turns starches into simple sugars

26
Q

lipase

A

turns triglycerides into fatty acids and glycerol

27
Q

dental plaque

A

a sticky, colorless biofilm that forms when bacteria in the mouth mix with sugars or starches.
-bacteria break down the starches, releasing acid, which releases calcium from the teeth causing tooth decay

28
Q

cross-sectional study

A
  • measures exposure/intervention and health outcome in a population at one point in time
  • strength of association between exposure and health outcome measured using Odds Ratio (OR)
  • if OR=1, then no association. if OR>1, increased odds of association. if OR<1, reduced odds
29
Q

prospective longitudinal cohort study

A

-measures exposure and outcome in a population over a period of time

30
Q

randomized controlled trial

A
  • experimental study wherein the exposure in controlled and the health outcome is assessed
  • participants are randomly assigned to a treatment or control group
31
Q

bolus

A

chewed food mixed with saliva

32
Q

after the bolus is compressed against the hard palate, where does it go?

A

the oropharynx (elevation of soft palate seals off nasopharynx so food doesn’t go into nose)

33
Q

what is the function of the epiglottis?

A

it folds down when the bolus comes to town and directs the bolus away from the trachea (so you don’t breathe in your food)

34
Q

what is swallowing?

A

-contraction of pharyngeal muscles to move bolus down out of oropharynx and into esophagus

35
Q

peristalsis

A
  • the involuntary constriction and relaxation of GI tract muscles, makes wave-like movements
  • pushes bolus from esophagus down into stomach (through the lower esophageal sphincter)
36
Q

achalasia

A

problem when lower esophageal sphincter doesn’t open up, and food can’t drop from esophagus into stomach

37
Q

gastroesophageal reflux disease

A

(acid reflux). problem when lower esophageal sphincter doesn’t close properly, and gastric juices and hydrochloric acid and stuff irritate the esophagus

38
Q

describe the movement of food from mouth to stomach.

A

mastication with teeth and saliva. cephalic phase. this mastication creates a bolus. the bolus is pressed up against the hard palate by the tongue. it then moves to the oropharynx, and elevation of soft palate blocks off the nasopharynx. meanwhile the epiglottis folds down over the trachea to make sure you don’t choke. then pharyngeal contractions move bolus from the oropharynx, through the Upper Esophageal Sphincter, into the esophagus. peristaltic waves in the esophagus move the bolus down, though the lower esophageal sphincter, and drops the bolus into the stomach.