Lecture 3: Anatomy and Physiology of the Digestive System Part 1, and types of study designs Flashcards
autonomic nervous system
- sympathetic and parasympathetic responses
- responsible for involuntary control
- cardiovascular, respiratory, urinary, digestive, reproductive functions
- adjusts electrolytes, nutrients and gases in body fluids
3 phases of digestion
cephalic, gastric and intestinal
How does autonomic nervous system work?
signals from the brain are carries to ganglia, which are then sent to peripheral target organs for either parasympathetic or sympathetic response
P or S?: heightened alertness
sympathetic response
P or S?: increased metabolic rate
sympathetic response
P or S?: decreased digestive and urinary functions
sympathetic response
P or S?: activation of energy reserves
sympathetic response
P or S?: increased respiration (rate and dilation of respiratory pathways)
sympathetic response
P or S?: increased heart rate and blood pressure
sympathetic response
P or S?: activation of sweat glands
sympathetic response
P or S?: decreased metabolic rate
parasympathetic response
P or S?: decreased heart rate and blood pressure
parasympathetic response
P or S?: increased secretion by salivary and digestive glands
parasympathetic response
P or S?: increased motility in the digestive tract
parasympathetic response
P or S?: increased blood flow in the digestive tract
parasympathetic response
P or S?: norepinephrine
sympathetic
P or S?: acetylcholine
parasympathetic
P or S?: greater divergence of reach to organs
sympathetic
autonomic tone
the background level of activity regulating the body (ie maintaining heart rate)
-parasympathetic dominates in resting conditions, sympathetic kicks into action in an emergency
accessory organs
- digestive organs through which food is not moved, like it is moved through the digestive tract.
- salivary glands, liver, pancreas, gall bladder
cephalic phase
-starts with anticipation of food and ends with swallowing
gastric phase
-the time during which food is in the stomach
intestinal phase
- starts when chyme enters the duodenum
- controls the rate of gastric emptying
- coordinates activities of intestinal tract, pancreas, liver and gallbladder
saliva
- made of water, glycoprotein (for viscosity), amylase, lipase
- essential for taste perception, antibacterial
- production lowers during sleep
amylase
turns starches into simple sugars
lipase
turns triglycerides into fatty acids and glycerol
dental plaque
a sticky, colorless biofilm that forms when bacteria in the mouth mix with sugars or starches.
-bacteria break down the starches, releasing acid, which releases calcium from the teeth causing tooth decay
cross-sectional study
- measures exposure/intervention and health outcome in a population at one point in time
- strength of association between exposure and health outcome measured using Odds Ratio (OR)
- if OR=1, then no association. if OR>1, increased odds of association. if OR<1, reduced odds
prospective longitudinal cohort study
-measures exposure and outcome in a population over a period of time
randomized controlled trial
- experimental study wherein the exposure in controlled and the health outcome is assessed
- participants are randomly assigned to a treatment or control group
bolus
chewed food mixed with saliva
after the bolus is compressed against the hard palate, where does it go?
the oropharynx (elevation of soft palate seals off nasopharynx so food doesn’t go into nose)
what is the function of the epiglottis?
it folds down when the bolus comes to town and directs the bolus away from the trachea (so you don’t breathe in your food)
what is swallowing?
-contraction of pharyngeal muscles to move bolus down out of oropharynx and into esophagus
peristalsis
- the involuntary constriction and relaxation of GI tract muscles, makes wave-like movements
- pushes bolus from esophagus down into stomach (through the lower esophageal sphincter)
achalasia
problem when lower esophageal sphincter doesn’t open up, and food can’t drop from esophagus into stomach
gastroesophageal reflux disease
(acid reflux). problem when lower esophageal sphincter doesn’t close properly, and gastric juices and hydrochloric acid and stuff irritate the esophagus
describe the movement of food from mouth to stomach.
mastication with teeth and saliva. cephalic phase. this mastication creates a bolus. the bolus is pressed up against the hard palate by the tongue. it then moves to the oropharynx, and elevation of soft palate blocks off the nasopharynx. meanwhile the epiglottis folds down over the trachea to make sure you don’t choke. then pharyngeal contractions move bolus from the oropharynx, through the Upper Esophageal Sphincter, into the esophagus. peristaltic waves in the esophagus move the bolus down, though the lower esophageal sphincter, and drops the bolus into the stomach.