Lecture 2A - Repro Anat Flashcards

1
Q

The endometrial cycle is divided into what two phases

A

Proliferative/follicular phase

Secretory/Luteal phase

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2
Q

Estrogen initiates what phase

A

Proliferative/follicular

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3
Q

Progesterone initiates what phase

A

Secretory/Luteal phase

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4
Q

Purpose of the proliferative phase

A

thickening of functional layer of endo

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5
Q

Purpose of secretory phase

A

Inc vascularity

Prep for implantation

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6
Q

Menses is in response to

A

Decrease in estro and progest

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7
Q

What stimulates formation of new layer of endo

A

Estrogen

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8
Q

At late proliferative phase endo measures up to ____mm

A

11 mm

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9
Q

When is the endo trilaminar

A

At late proliferative

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10
Q

What hormones helps prepare the endo to accept the blastocyst

A

Progesterone (mostly)

Estrogen

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11
Q

The endometrium is hyper/hypoechoic at secretory phase

A

hyperechoic

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12
Q

Explain how non-fertilization leads to menses

A

No pregnancy = no hCG
Corpus luteum degenerates
Prog and estro levels decrease
Endo breaks down

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13
Q

First menstrual period is called

A

menarche

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14
Q

Ovarian cycle phases (3)

A

Follicular phase
Ovulatory phase
Luteal phase

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15
Q

Explain the follicular phase

A

FSH released by the anterior pit stimulates growth of a group of primary follicles (these produce estrogen)
One follicle becomes the dominant follicle which becomes Graafian follicle -moves toward the ovarian wall

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16
Q

In the ovulatory phase, what causes the follicular and ovarian wall to rupture

A

LH surge

17
Q

Mittelschmerz

A

Pain during ovulation

18
Q

What happens in the luteal phase

A

Graafian cavity collapses and forms corpus luteum

19
Q

What does the corpus luteum secrete

A

mostly progesterone

estrogen

20
Q

How long is the luteal phase

A

12-14 days unless it receives hCG from gest. sac

21
Q

What does the corpus luteum turn into if not fertilized?

A

Corpus albicans

22
Q

What hormone does the hypothalamus release and what is the target cell

A

GnRH - anterior pituitary

23
Q

What hormone(s) do the anterior pituitary release?

A

FSH

LH

24
Q

Target cells of FSH, and what does that stimulate?

A

ovarian follicles - follicle growth

stimulates estrogen production

25
Q

target cells of LH

A

ovarian follicles and corpus luteum

26
Q

What does LH stimulate?

A

ovulation
CL development
estrogen + progesterone production

27
Q

The ovaries secrete what hormone(s)

A

Estrogen

Progesterone

28
Q

What type of feedback does estrogen cause during most of the cycle? What is the target(s)?

A

Estrogen causes negative feedback to hypo (GnRH) and anterior pit (LH, FSH)

29
Q

Estrogen causes positive feedback to hypo and anterior pit at what point in the cycle

A

day 12-14

30
Q

What type of feedback does progesterone do?

A

Negative feedback on hypo and anterior pit

31
Q

What do low levels of estrogen and progesterone do?

A

positive feedback to hypothalamus, which increases GnRH, LH, FSH

32
Q

Dominant follicle into Graafian follicle caused by

A

FSH

33
Q

Ovulation caused by

A

Threshold high level of estrogen causes LH surge - enzymes released degrade follicular wall

34
Q

LH following high level estrogen surge stimulates what

A

Formation of CL from collapsed dominant follicle

35
Q

CL produces

A

High levels of estro and progest

36
Q

What do high levels of estro and progest do feedback wise?

A

Activate negative feedback to hypothal, ant pit - no FSH and LH