lecture 26 - vitamins and minerals Flashcards
what are vitamins
organic substances = made by plants and animals
- always contain carbon as they are organic
how are water soluble vitamins absorbed, secreted and stored
absorbed in portal blood, excreted in urine when plasma levels exceed renal thresholds
- not absorbed in large quantities
what system do fat soluble vitamins enter and how are they stored
initially enters the lymphatic system as part of chylomicron
- stored in greater quantities = mainly liver, adipose tissue and cell membranes
what are minerals
inorganic elements = come from soil and water, absorbed by plants or eaten by animals
what are minerals responsible for
- structural functions involving skeleton and soft tissues
- regulatory functions including neuromuscular transmission, blood clotting, oxygen transport and enzymatic activity
what are macro molecules
Ca, p, Mg, Na, K, Cl
- required in amounts greater than 100mg/day
what are minor minerals
Fe, Zn, Se, I, Cu, Cr, Mn, Mo
required in less than 100mg/day
what do enzymes do
make reaction go faster by lowering activation energy
what do co enzymes do
are organic carrier molecules
(involved in transferring things from one molecule to another)
what are co factors
more general term for small molecules required for the activity of their associated enzyme
- not strictly carrying something - may stabilise enzyme or substrate
what is thiamine
serves as a co enzyme in the form of thiamine pyrophosphate (TPP) in a variety of metabolic processes
examples of where thiamine serves as a co factor in carbohydrate metabolism
pyruvate dehydrogenase = converting pyruvate to acetyl CoA
a-Ketoglutarate dehydrogenase = converting a-Ketoglutarate to succinate in the citric acid cycle
what does a thiamine deficiency cause
adverse consequences on energy production and nutrient metabolism = affecting cardiovascular, muscle tone and immune systems
differences between wet and dry beriberi
in rarer cases, wat beriberi can cause congestive heart failure that leads to edema (overabundance of fluid in the tissues)