Lecture 26 Food Allergy in Children Flashcards

1
Q

Mast cell degranulation rapid releases what 3 substances

A

Histamine
Tryptase
Hydrolase

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2
Q

What do mast cells degranulation later release

A
Inflammatory mediators
Prostaglandins
Leukotrienes
PAF
Cytokines
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3
Q

What is the function of Histamine

A

Bronchial smooth muscle contraction
Vasodilation
Separation of endothelial cells
Pain and itching

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4
Q

Name 3 investigations that can be carried out for allergies

A

Skin prick testing
IgE
Oral food challenge

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5
Q

What is the treatment for Urticaria and Angioedema

A
H1 antihistamine
High dose antihistamine
Leukotriene antagonist
Corticosteroids
Tranexamic Acid
Anti IgE monoclonal antibody
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6
Q

What is the treatment for Anaphylaxis

A

Adrenaline pen

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7
Q

What is the action of adrenaline

A

Reverses vasodilation
Increases peripheral vascular resistance
Decreases angioedema
Causes bronchial dilation

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