Lecture 26 Food Allergy in Children Flashcards
1
Q
Mast cell degranulation rapid releases what 3 substances
A
Histamine
Tryptase
Hydrolase
2
Q
What do mast cells degranulation later release
A
Inflammatory mediators Prostaglandins Leukotrienes PAF Cytokines
3
Q
What is the function of Histamine
A
Bronchial smooth muscle contraction
Vasodilation
Separation of endothelial cells
Pain and itching
4
Q
Name 3 investigations that can be carried out for allergies
A
Skin prick testing
IgE
Oral food challenge
5
Q
What is the treatment for Urticaria and Angioedema
A
H1 antihistamine High dose antihistamine Leukotriene antagonist Corticosteroids Tranexamic Acid Anti IgE monoclonal antibody
6
Q
What is the treatment for Anaphylaxis
A
Adrenaline pen
7
Q
What is the action of adrenaline
A
Reverses vasodilation
Increases peripheral vascular resistance
Decreases angioedema
Causes bronchial dilation