Lecture 25 Juvenile Idiopathic Arthritis Flashcards
What is the clinical presentation of JIA
>6 weeks Morning stiffness or swelling Refusal to walk Rash/fever Fatigue Poor appetite/weight loss
Psoriasis is seen in what type of JIA
Psoriatic arthritis
HLA-B27 positive male beginning after 6th birthday would indicate what type of JIA
Enthesitis related arthritis
Early onset Pauciarticular JIA is seen in how many joins
4 or less
Early onset Pauciarticular JIA is seen commonly in___
Girls
What limbs are involved in Early onset Pauciarticular JIA
No hip
Knees, ankle, hands, feet and wrist
is Early onset Pauciarticular JIA ANA positive or negative
Positive
Late onset pauciarticular JIA is seen commonly in__
Boys over 8 years
What is the joint involvement of late onset pauciarticular JIA
Hip
Is late onset pauciarticular JIA ANA positive or negative
Negative
How many joints are involved in polyarticular JIA
5
Is polyarticular JIA more common in boys or girls
More common in girls
Serpositive polyarticular JIA is more common
Children over 8
Seronegative polyarticular JIA is more common in
Children under 5
Name features of Enthesitis related JIA
Boy >8 years HLA B27 positive Uveitis Inflammatory spinal pain Sacroiliac joint tenderness
Name the features of Psoriatic JIA
Family history of Psoriasis
Dactylitis
Onycholysis
HLA B27
What are the symptoms of systemic JIA
Arthritis Fever Salmon pink erythematous rash Lymphadenopathy Hepatomegaly/splenomegaly
What is the common DMARD used to treat JIA
Methotrexate
If the patient fails to respond to DMARDs what is the next line of treatment
Biologic agents
Anti-TNF