Lecture 26: Citric Acid Cycle Flashcards
pyruvate enters the citric acid cycle after glycolysis if __ condition present
aerobic
pyruvate is converted to __ in preparation for the citric acid cycleq
acetyl CoA
in the citric acid cycle, acetyl CoA is transformed in energy precursors __ and __
NADH and FADH2
electron transport from the energy precursors leads to the ___ to produce ATP
phosphorylation of ADP
the main function of the citric acid cycle is to harvest __ from carbon fuels
high-energy electrons
the citric acid cycle is the central pathway for ___ all metabolic fuels
oxidizing
t/f citric acid cycle connects carbohydrate, fat, and protein metabolism
true
most of the energy made from substrate oxidation in the citric acid cycle is stored in __
reduced electron carriers: NADH and FADH2
how many (net) ATP are made per glucose in the citric acid cycle?
2
how many ATP are made after the ETC for on glucose?
34
another important role of the citric acid cycle is the production of intermediate compounds important in the making of things like __ and __
amino acids and fatty acids
in eukaryotes, glycolysis occurs in the __
cytoplasm
in eukaryotes, the Krebs cycle occurs in the
mitochondria
in eukaryotes the ETC takes place in the __
inner crystal of the mitochondria
in prokaryotes, all steps of metabolism occur in __ and __
cytoplasm and PM
why is the Krebs cycle called a cycle?
b/c the starting material oxaloacetate is regenerated at the end of the cycle
what is the first product of the Krebs cycle?
citric acid
why is the Krebs cycle referred to as the trim-carboxylic acid cycle?
citric acid contains three carboxylic acid groups
3C pyruvate is converted to 2 carbon that is linked to the coenzyme by the enzyme __
pyruvate dehydrogenase
t/f pyruvate processing is a redox reaction
true
what are the co-products of pyruvate processing?
CO2 and NADH
coenzyme A is a __ molecule
high energy carrier
t/f CoA carriers acetyl in both catabolic and anabolic processes
true
the attachment of CoA to acetyl allows the acetyl to attach to
oxaloacetate
from one citric acid cycle the following products are made:
1 ATP 3 NADH (+1 NADH from pyruvate oxidation) 1 FADH 2 CO2 regenerated oxaloacetate
how many rounds of the Krebs cycle,e are needed to completely oxidize one molecule of glucose?
2
in an efficient cell, as many as __ ATP can be produced by cell respiration
38
