Lecture 25 - Valve Heart Disease

Question 1

Diastolic murmurs?

Answer 1

indicate mitral or tricuspid stenosis; or aortic/pulmonary incompetance

Question 2

Systolic murmurs?

Answer 2

indicate mitral or tricuspid incompetance; or aortic/pulmonary stenosis

Question 3

Developmental defects of connective tissue?

Answer 3

stenosis of pulmonary or aortic, leaflet abnormalities, floppy mitral valve

Question 4

Dystrophic calcification?

Answer 4

injured tissue developing calcium deposits, can travel e.g. annular calcification of mitral valve, stenosis of aortic valve

Question 5

Acute Endocarditis?

Answer 5

high virulence organism (e.g. Staph Aureus), prev. normal valve, destructive, high mortality)

Question 6

Sub-acute endocarditis?

Answer 6

low virulence organism (e.g. Strep viridans), prev. abnormal valve, insidious

Question 7

Non-bacterial thrombotic endocarditis?

Answer 7

deposition of fibrin/platelets on heart valves, no pathogens, possible occurance during hypercoagulable state e.g. cancer

Question 8

Carcinoid tumours?

Answer 8

tumours from neuroendocrine cells, form plaque-like thickening of right heart containing smooth m. - affects tricuspid and pulmonary valve