lecture 24 - sae 3 Flashcards
what does reading the genome begin with
awh
what has led to generation of a lot of genome sequence
a
what reveals TE abundance
a
How do we start to understand all this sequence info
a
describe looking for orfs
a
what proves it is part of real gene
a
describe looking for cdnas
a
what is best evidence that orf is part of a real gene
a
what else do we check for as evidence that orf is part of real gene
a
describe interpretation of genome sequence
a
Why does identification of a cDNA that maps to a predicted ORF provides strong evidence that the ORF is part of a real gene?
z
After all this analysis, how many genes are there?
a
describe structure of human genome
a
if 3% of dna in human genome represents exons of protein coding genes why does only 1% encode protein sequences
a
what is rare vs common in genome
a
what are comparative genomics
a
name the 3 diff types of comparisons
a
comparing within species = describe comparison of sequences within a genome
a
comparing within species = identification of disease genes through genome comparisons often involves what and explain
a
describe dog genome project
a
describe Insights from comparing genomes within a species
a
what does comparison of genomes between species shows
a
comparing between species = what is synteny
a
comparing between species = phylogenic inference
a
give ex of phylogenic inference use
a
describe yolks
a
describe comparative Genomics and Human Medicine
a
A child normally inherits one copy of each chromosome from each parent. But….
a
How can two chromosomes from the same parent end up in the same F1 individual?
a
what is upd generated by
a
are all chromosomes equally likely to be found in udp
a
describe genetics and genomics together
a
