lecture 22 Flashcards
what are mutations
a
where do most mutations occur
a
what types of mutations can be passed on
a
describe inherited mutations
a
Why will only half of the F1 individuals carry the mutation?
a
what is a mutation
a
what can mutations be
a
Explain how mutations can be a source of genetic variation
a
name the 3 types of scales of mutations
a
describe chromosomal mutation
a
describe insertional mutation
a
describe point mutation
a
name categories of point mutations - 2
a
describe base sub point mutations
a
describe the consequences of point mutations in open reading frames - synonymous mutations
a
describe the consequences of point mutations in open reading frames - nonsynonymous mutations
a
describe the consequences of point mutations in open reading frames - nonsense mutations
a
describe the consequences of point mutations in open reading frames - frameshift mutations
a
describe what happens when single base sub
a
describe what happens when single base insertion or deletion
a
do all point mutations have same effect and explain
a
describe wild type function
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describe loss of function
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describe gain of function
a
give ex of loss of function
a
give ex of gain of function
a
can sequences in non coding regions be important for gene function?
a
describe consequences of point mutations in non-coding regions
a
Why do some patients with a mutation in the PBRM1 gene have a worse prognosis?
a
describe ex of BAP1
a
describe Effect of point mutations on a gene’s mRNA and protein products
a
describe consequences of point mutations within genes
a
can mutations be spontaneous or induced
a
describe origins of spontaneous mutations
a
describe origins of spontaneous mutations - errors in base pairing
a
