LECTURE 23 DISEASE Flashcards
TUBERCULOSIS is also known as
mycobacterium tuberculosis
how long does it take to grow
2 weeks to form a colony
who won the nobel prize for tubeculosis
Robert Koch in 1882
how is tuberculosis is transmitted
person to person sopread
hwo is tb a professional pathogen
it is not supposed to be in the body so if it is, it causes diseases
Steps to get infected by TB
host inhales
immune cells recruited, phagocytose bacteria
bacteria get to lung tissue
bacteria survive, replicate
bacteria is replicated in
ghon complex (calcified)
characteristics of tb active disease
months to decades
once immune cells faul to contain replication
it disseminates into lungs, bloodstream and other organs
who are most susceptible to tubeculosius
homeless, elderly, malnourished, prisons
How is tb detected
PPD
Chest X-ray
Blood culture
DNA probes
How effeicient is BCG
more efficient in children than adult. 950-80 % efficient)
what drug is used to treat tb
streptomycin
which form of tuberculosis is tough to treat, resistant to multiple drigs and have inadequate therapy
MDR-TB
Leprosy is also known as
Hansen’s disease (Mycobacterium leprae)
how is leprosy contacted
prolonged close contact, nasal secretions