LECTURE 23 DISEASE Flashcards

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1
Q

TUBERCULOSIS is also known as

A

mycobacterium tuberculosis

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2
Q

how long does it take to grow

A

2 weeks to form a colony

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3
Q

who won the nobel prize for tubeculosis

A

Robert Koch in 1882

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4
Q

how is tuberculosis is transmitted

A

person to person sopread

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5
Q

hwo is tb a professional pathogen

A

it is not supposed to be in the body so if it is, it causes diseases

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6
Q

Steps to get infected by TB

A

host inhales
immune cells recruited, phagocytose bacteria
bacteria get to lung tissue
bacteria survive, replicate

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7
Q

bacteria is replicated in

A

ghon complex (calcified)

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8
Q

characteristics of tb active disease

A

months to decades
once immune cells faul to contain replication
it disseminates into lungs, bloodstream and other organs

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9
Q

who are most susceptible to tubeculosius

A

homeless, elderly, malnourished, prisons

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10
Q

How is tb detected

A

PPD
Chest X-ray
Blood culture
DNA probes

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11
Q

How effeicient is BCG

A

more efficient in children than adult. 950-80 % efficient)

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12
Q

what drug is used to treat tb

A

streptomycin

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13
Q

which form of tuberculosis is tough to treat, resistant to multiple drigs and have inadequate therapy

A

MDR-TB

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14
Q

Leprosy is also known as

A

Hansen’s disease (Mycobacterium leprae)

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15
Q

how is leprosy contacted

A

prolonged close contact, nasal secretions

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16
Q

incubation period of leprosy

A

3-5 years (up to 20 years)

17
Q

what type of pathogen is leprosy

A

obligate intracellular pathogen ( must get into the cell)

18
Q

where does leprosy invade

A

invade nerve or skin cells

19
Q

describe tuberculoid keprosy

A

hypersensitivity reaction, skin lesions and dmaage to nerves, skin

20
Q

which type of leprosy invade skin schwann cells covering nerves

A

lepromatous leprosy

21
Q

rabies is also known as

A

rhabdovirus (virus)