Lecture 23 - Chance 1 Flashcards
What is internal validity
The extent to which the study findings are free from alternative explanations (bias, confounding)
What is external validity
The extent to which study findings can be applied to broader populations
What is sampling error
The error that occurs just by chance when a sample isn’t perfect representation of population. Commonly just called chance
What can be done about the sample error
Increasing the size of the study sample when randomly sampling
What does increasing the sample size do
- Reduces sample variability
- Increase likelihood of getting a representative sample
- Increases precision of parameters estimate
How to measure influences of sampling error
Using confidence intervals
What does a 95% C.I represent
It represents the range within which the true population parameter lies 95% of the time if repeated sampling occurs
what are C.I
A more common and intuitive, less-precise, interpretation.
- We are 95% confident that the true population value lies between the limits of the confidence interval.
Interpretation of C.I
We are 95% confident that the true value of parameter (OR) lies between the upper and Lower limit.
Clinical importance of C.I
C.I can help us decide whether the study findings are clinically important
Parameter
The true value of the measure in the population that the study is trying to discover
Estimate
The measure found in the study sample, sometimes referred to as the point estimate