lecture 22: population genetics 2, natural selection, and adaptation Flashcards

1
Q

consanguinity

A

property of being descended from the same ancestor as another person

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2
Q

why is inbreeding genetically bad

A
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3
Q

identity by descent

A

inbreeding increases the percent homozygous because offspring can inherit two identical copies of an allele from the same ancestor

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4
Q

inbreeding coefficient

A

the probability that a child born to related parents will be IBD at any locus

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5
Q

calculating inbreeding coefficient

A
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6
Q

malaria

A
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7
Q

sickle cell resistance to malaria

A
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7
Q

no selection

A

new allele under neutral evolution (no selection) rises and falls in prevalence by chance

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8
Q

positive selection

A

new allele under positive selection rises rapid

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9
Q

balancing selection

A

new allele under balancing selection rises rapidly in prevalence in the population up to an equilibrium point

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10
Q

negative selection

A

new alleles under negative selection will get rapidly weeded out of the population

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11
Q

how did we find genes

A
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12
Q

human and chimp genomes

A
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13
Q

why is purifying selection important

A
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14
Q

how to detect positive selection

A
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