Lecture 2.10 Viruses Flashcards

1
Q

What are the features of rotavirus?

A

Causes diarrhoea in kids under 5, vaccine not widely used, need rehydration, virus has multiple capsid shells to protect it moving through the GIT

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2
Q

What are the features of HIV/AIDS?

A

Virus grows in immune cells and chips away at CD4T cells - immunodeficiency. Reduction in deaths due to combined antiviral treatment, 70% go global AIDS population (25.8 mil) in sub saharan africa, only 54% of people with AIDS know they have it

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3
Q

What are the features of viruses?

A

Floating around - have to invade host cell to replicate, have a capsid shell for protection and sometimes an envelope surrounding that (formed by host cell membrane) and a matrix - connects the envelope and capsid glycoproteins. Virus can be +ve sense (mRNA) or -ve sense (complementary strand)

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4
Q

What is capsid symmetry, the types, and the viruses?

A

Capsid symmetry protects the viral genome from nucleosomes breaking it down

  • Icosahedral: adenovirus, herpes, pailloma
  • Helical: influenza, mumps
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5
Q

What is poxvirus?

A

Largest virus, has 130kbp and can form >100 proteins

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6
Q

What are arboviruses?

A

Infect insects that ingest vertebrae blood, replicate in insect and transmitted by bite

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7
Q

What does hepatitis target and how do the types move through the body?

A

Targets the liver
A & E - enteric
B, C & D - via blood or sex

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8
Q

What are the features of SARS?

A

Severe acute respiratory syndrome, pneumonia, small epidemic pop but fast spreading, controlled by public health measures, grew in cultured vero cells

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