Lecture 2 - Immun. Overview

Question 1

Innate immunity:

Answer 1

Does not require specific recognition of each pathogen. Works the same no matter what the problem is and works the same no matter how many times it has encountered the problem
_FAST

Question 2

What cells are common in Acute inflammation

Answer 2

Plasma proteins
Mast cells
Neutrophils

Question 3

What cells are common in Chronic inflammation

Answer 3

Cell proteins
Lymphocytes
Macrophages

Question 4

Adaptive immunity (or acquired, specific immunity):

Answer 4

Uses specific lymphocytes (B and T lymphocytes) that are selected during infection because they recognize a particular microbe but are useless against most othe rmicrobes

Question 5

S. pneumonia, like many bacterial pathogens, posses what that blocks phagocytosis by PMNs and macrophages

Answer 5

An outer capsule

Question 6

What does it mean to be immunogenic?

Answer 6

Induces an adaptive immune response

Question 7

What is opsonization

Answer 7

Process of coating antigens with antibodies to enhance phagocytosis

Question 8

T or F, Cytokines are helpful but not usually required for a full and effective adaptive immune response

Answer 8

False, They are usually required!

Question 9

What is S. pneumoniae’s major virulence factor?

Answer 9

CHO-capsule as it protects the bacterium from innate phagocytic activity

Question 10

Name 6 defense molecules

Answer 10

1. Immunoglobulin (Antibody)
2. T-Cell Receptor
3. Histocompatability Ag (presenter mol.)
4. Cytokines (Lymphokines monokines etc.)
5. Fc Receptors
6. Cytokine receptors

Question 11

T or F, B cell divides into a large clone of identical ‘daughter’ lymphocitic cells

Answer 11

True