Lecture 2- EC50 and partial agonists

Question 1

… refers to the dose of a drug that produces 1/2 maximal effect

Answer 1

EC50

Question 2

EC50 describes the quantitative aspects of drug….

Answer 2

action

Question 3

… is one factor that determines the concentration dependence of drug action. The ability to confer the response (known as ….) is another factor

Answer 3

binding affinity

efficacy

Question 4

…. refers to the relative ability of a drug to confer an effect. The …. of a drug (the concentration range where it works) is determined by both its binding affinity as well as its efficacy

Answer 4

potency

Question 5

drugs with insufficient … will be partial agonists regardless of how well the bind with their receptor.

Answer 5

efficacy

Question 6

drugs with no efficacy that bind to the receptor will be …

Answer 6

antagoists

Question 7

characterize receptors by their …., not the nature of their …

Answer 7

pharmacology

physiological response