Lecture 18- Motor control, cortex and allied structures Flashcards

1
Q

What are the different levels of integration?

A

Spinal cord- reflexes
Subcortical- medial/ventral sc paths, medial cerebellum - reproduction
Cortical- lateral sc pathways, lateral cerebellum- science, art etc

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2
Q

Rubrospinal tracts

A

originates from the red nucleus, a midbrain structure.
as the fibres emerge, they decussate (cross over to the other side of the CNS), and descend into the spinal cord. Thus, they have a contralateral innervation.

thought to play a role in the fine control of hand movements

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3
Q

Reticulospinal tracts

A
  • The medial reticulospinal tract arises from the pons. It facilitates voluntary movements, and increases muscle tone.
  • The lateral reticulospinal tract arises from the medulla. It inhibits voluntary movements, and reduces muscle tone.
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4
Q

Vestibulospinal tracts

A

Medial and lateral- arise from vestibular nuclei of the medulla, travel ventrally in spinal cord
Innervate neck and antigravity muscles (flexors of arm, extensors of leg)

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5
Q

Tectospinal tract

A

Originates in superior colliculus of midbrain and controls eye movements.

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6
Q

Where are the sensory and motor homunculi located?

A

Postcentral gyrus

Precentral gyrus

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7
Q

What are the roles of the premotor cortex and supplementary motor areas?

A

Premotor- set posture appt. to movement, aid in selecting movement
Supplementary- integrating COMPLEX, PLANNED patterns of movement

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8
Q

Corticospinal tracts

A

Main descending tracts responsible for motor control
Most travel from cortex to pyramids in medulla, > lateral corticospinal tracts to innervate distal muscles responsible for fine control
ventral corticospinal tracts control proximal muscles responsible for posture

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9
Q

Where do motor neurons innervating face travel in

A

Corticobulbar tracts
30% pyramidal neurons from primary motor cortex, 30 from premotor/supp and from 40 in partietal assc. area/ primary somatosensory area

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10
Q

What is the final common path for UMN

A

LMNs- neurons eventually innervate a motor unit which can receive input from many neurons

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11
Q

UMN lesions

A

most common is cerebral stroke- removes higher control over midbrain reflexes, can result in hyperactive stretch reflexes, spastic rigidity of flexors in UL and extensors in lower limbs and positive babinski’s sign

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12
Q

What are the 5 components of the basal ganglia?

A

5 pairs of nuclei
Caudate nucleus, putamen, globus pallidus, substatia nigra and subthalamic nuclei
Feed output to motor/assc. of cerebral cortex via thalamus and receive cortical input

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13
Q

What are some conditions associated with the basal ganglia?

A

Parkinsons- excessive suppression
Huntington’s, parkinsons, tourettes- excessive release
Impacts preprogrammed movement and behaviours (speech in tourettes)

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14
Q

Putamen circuit

A

Feeds via loop from cortex > putamen > GP > SN > thalamus > cortex
Problems give rise to twisting, bending movements of hands face arms or neck, flailing of whole limb and flickering of hands and face

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15
Q

Caudate circuit

A

Cognitive control of motor pattern sequences- maintained by projection between SN and striatum, problems often arise duet to hyperactivity or depression of dopaminergic connetction between them

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16
Q

What causes hypo/hyperkinetic aspects in parkinsons

A

degeneration of dopaminergic neurons between SN and striatum- less excitation, less inhibition of GP, greater inhibition of thalamaic projection to cortex
Inability to initiate movements- or cog wheel rigidity/tremor at rest (Hyper)

17
Q

What causes unintentional movements in huntingtons

A

Breakdown of cholinergic/ GABAergic pathways in basal ganglia (athetosis, ballimus and chorea)

18
Q

What causes effects of tourettes

A

Excess dopamine, tics due to unintentional release of preprogrammed behaviours/movements

19
Q

Cerebellum what is the anatomy and function

A

2 lobes- innervated from cortex, brain stem and periphery (proprioception, skin, ear, vestibular apparatus, eyes) > into cortex brainstem reticular formation and red nucleus
Coprocessor- corrects errors in movmvent

20
Q

How does the cerebellum control/ correct movement

A

Vestibulocerebellum- equilibirum and eye movement
Spinocerebellum- comparing motor cortex (what areas want to do) with what it is actually doing
Cerebrocerebellum- most lateral part- planning/preprogramming movements

21
Q

What occurs with cerebellar problems?

A

Inaccurate movements/ difficulty in maintaing stable posture/ visual fixation (kinaesthetic learning aswell)
V/SC- wide stance, swaying, inappropriate nystagmus, ataxic gait
CC- dysmetric movements, decomposition of movements, intention tremor, delay in initiation of movement