Lecture 16

Question 1

Lipophilic (hydrophobic)?

Answer 1

Having an affinity for, tending to combine with, or capable of dissolving in lipids

Question 2

Lipophobic (hydrophilic)?

Answer 2

Having an affinity for, tending to combine with, or capable of dissolving in aqueous solutions

Question 3

Disperse system?

Answer 3

One component (dispersed phase) dispersed through the other (continuous phase) - phases don’t change!

Question 4

Lyophobic?

Answer 4

Having an aversion for the solvent type

Question 5

Lyophilic?

Answer 5

Having an affinity for the solvent type

Question 6

Suspension in pharmacy?

Answer 6

Solid material (usually the drug) does not dissolve in the liquid phase. The drug remains as solid particles. These particles are distributed throughout the liquid phase. Technically, a suspension describes a dispersion of solid materials (the dispersed phase) in liquid (continuous phase). E.g. Milk of magnesia, kaolin suspension

Question 7

Disadvantage of suspension?

Answer 7

Uniformity of suspension can change over time (need to shake well) - heterogeneous