Lecture 13 Cartilage and bone Flashcards

1
Q

Cartilage Cell Type

and Types

A

Chondrocytes
Hyaline, Elastic and Fibrocartilage

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2
Q

Bone Cell Type(s) and Types

A

Osteoclast, Osteocytes and Osteoblast
Woven/lamellar

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3
Q

What type of cells are spaces are chondrocytes found in

A

Lacunae

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4
Q

What is the white

A

Lacunae

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5
Q

What are these “clusters called” and where are they found?

A

Isogenous groups and grow in intersital growth… Chondrocytes..Mitotic growth

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6
Q

What is the ECM of Cartilage composed of?

A

GAGS, Proteoglycans, TYPE 2 Cartilage
AVASCULAR relys on diffusion

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7
Q

What is the black arrow and what type of growth?

A

Perichondrium allows for appositional growth,

DENSE IRREGULAR.

Not found in Fibrocartilage or Articular cartilage

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8
Q

What is this and where is it found

A

Hyaline Cartilage and found in most areas like joints and trachea

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9
Q

What is this?

A

Fibrocartilage found in the vertebral spine

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10
Q

What type of cartilage is this and where is it found

A

Elastic Cartilage and found in the ears

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11
Q

What is the purpose of Hyaline Cartilage

A

FXN: resist compression, EXM attracts water, Articular Cartilage is hyaline cartilage of joints.

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12
Q

What is this

A

Articular Cartilage(Hyaline)
Glassy Apperance, pink to nlue stain.
**NO PERICHONDRIUM **

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13
Q

What is this

A

Articular Cartilage(Hyaline)
Glassy Apperance, pink to nlue stain.
**NO PERICHONDRIUM **

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14
Q

What is this.
Hint notice the top

A

Hyaline Cartilage
HAS PERICHONDRIUM

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15
Q

What is this? and FXN

A

elastic cartilage uses Orcein and Hematoylin/Orcein to stain

FXN+ Elastic support

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15
Q

What is this? and FXN

A

elastic cartilage uses Orcein and Hematoylin/Orcein to stain

FXN+ Elastic support

16
Q

What is this? and its FXN

A

Fibrocartilage and used for Tension and Compression

NO PERICHONDRIUM
Chonrdocytes line up in a row

17
Q

Cartilage can resist tremendous compressive force, but once injured, has limited ability to repair due to _______

____ will result in _____(Scar tissue)

A

Avascular
Perichondrium will result in scar tissue.

18
Q

Woven (Immature) Bone

A

Initial bone formed; fracture repair
* Poorly organized type I collagen
* Grows rapidly

19
Q

Lamellar (Mature) Bone

A

Distinct layers (lamellae) present
* Well-organized type I collagen
* Grows slowly

20
Q

1 and 2

A

Lamellar and Woven

21
Q

What is this

A

Haverisan Canal and Osteon

22
Q

Basic unit of Bones

A

Osteons (Secondary osteons, Haversian System)
* basic unit of bone
* rings of lamellar bone around a central canal

23
Q

What is the purpose od teh central Canal

A

contains blood vessel & nerves
* diffusion through canaliculi

24
Q

Which is the perforating Canal and what is its purpose

A

connect central canals with each other & vessels in the periosteum and marrow cavity
* perpendicular to central canals

25
Q

What are the Black Dots.

A

Lacunae for bones

26
Q

What is the overall and its two layers

A

Periosteum
Outer fibrous(dense CT) and Inner cellular(Stem cells)

27
Q

What type of fibers attach muscle to bone?

A

Sharpey

28
Q

What are the yellow lines?

A

Endosteum a monolayers of cells, STEM CELLS

29
Q

MSC lineage.

A

Osteoprogenitor cell –> Osteoblast –> Osteocyte(In matrix)

30
Q

HPS Lineage

A

HPSC to OsteoClast

31
Q

What is this

A

Osteoblast

32
Q

What are these

A
33
Q

What do osteoblast secete

A

Osteoid

34
Q
A

Osteoblast
Osteoid
Mineralizing bone
Ostocyte

35
Q

Where do osteoclast lay at?

A

Reside in resorption cavities (Howship’s lacunae)

36
Q

Osteoclast Zones
Which is the clear Zone(site of Adhesion)
Ruffled zone((Folded Plasma)

A

Black is ruffled and Green is clear zone
. Lysosomal enzymes help break down

37
Q

PTH vs Calcitonin

A

PTH helps increas CA2 levels binds to osteoblast.

Calictonin Helps to decrease calciulm levels inhibts by binding to osteoclast