Lecture 10: Peripheral Blood Flashcards

1
Q

Three layerts of blood draw

A

55% Plasma
1% Buffy(WBC)
45: hemo(Packed RBCS)

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2
Q
A

Erythrocytes (RBCs)
Leukocytes (WBCs)
Blue Arrow: Platelets (thrombocytes)

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3
Q
A

Erythrocytosis – ↑ % RBCs

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4
Q
A

Anemia – ↓ % RBCs

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5
Q
A

Leukocytosis – ↑ % WBCs

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6
Q
A

Spherocytosis

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7
Q
A

Lacks nucleus & most organelles (therefore not a cell, so an erythrocyte is called a formed element)

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8
Q
A

Platelet: 2nd most abundant ~2um
Blood clotting(hemostatis)

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9
Q

Thrombocytopenia

A

is characterized by low levels of platelets. Symptoms may include easy bleeding or bruising.

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10
Q

Granules are secreted for:

A

Coagulation
▪ Platelet adhesion
▪ Vasoconstriction
▪ Blood vessel repair

E- even dense

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11
Q
A

Neurtophill

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12
Q
A

Eosinophil

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13
Q
A

Basophils

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14
Q
A

Lympocytes

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15
Q
A

Monocyte

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16
Q
A

Granulocyte: neutrophil
BILOBED NUCULES

17
Q

Neutrophils FXN

A

Most Abundant. Phagocytoses bacteria and O2 depending.

two types of granules: Azurophillic(lysosomes) and Specific e-dense

18
Q

Granulocyte: eosinophil

A

Bi- (or tri-) lobed nucleus
Specific granules –
Electron-dense crystalloid body
**Major basic protein **released by exocytosis –
has toxic effect on parasites

19
Q
A

eosinophil

20
Q
A

eosinophil

21
Q

elevated eosinophil counts in a blood panel may indicate of

A

parasitic infection

22
Q

Granulocyte :basophil

A

Least numerous leukocyte or blood cell
hypersensitivity (allergic) reaction…Similar to MAST
Bi- (or tri-) lobed nucleus
Heparin (anticoagulant [GAG]) Histamine (↑ blood flow)

23
Q
A

Basophil

24
Q
A

Basophil

25
Q

Agranulocyte: lymphocyte

A

B lymphocyte – secrete antibodies as plasma cells
T lymphocyte – recruit & activate phagocytic cells
Natural killer cell – kill virally-infected or some cancer cells

26
Q
A

Lymphocyte: Basic cytoplasm small amount of cyto compared to nucules

27
Q
A

Lymphocyte

28
Q

Precursor to macrophages

A

monocytes
“Fat” C-shaped nucleus

29
Q
A

Macrophage to monocyte

30
Q
A

A
B. RBC
C. Basophil
D. Eosniophil
E. Neutrohpil
F. Lympohocyte
G. Macrophage