Lecture 12 Immune System

Question 1

Certain diseases block lymphatic circulation and trap lymph in tissues resulting in localized swelling

Answer 1

lymphedema

Question 2

Answer 2

Innate immunity

Question 3

Adaptive immunity

Answer 3

Question 4

B lymphocytes are responsible for —— immunity

Answer 4

humoral (antibody)

Question 5

T lymphocytes are responsible for _________immunity (need activation by APC)

Answer 5

cell- mediated

Question 6

B (lymphocytes) cells mature in

Answer 6

bone marrow

Question 7

T (lymphocytes) cells mature in

Answer 7

thymus

Question 8

Secondary lymphoid organs

Answer 8

Sites of B & T cell activation
Diffuse lymphoid tissues, tonsils, lymph nodes, spleen

Question 9

Answer 9

Bone Marrow
look for megakarocytes(Yellow)
Hemopoietic cells and sinusodial cap

Question 10

ancer of red marrow. Normal blood cell counts are reduced resulting in fatigue, easy bruising, and increased risk of infections.

Answer 10

Leukemia

Question 11

absent or hypoplastic thymus results in T cell immunodeficiency with increased risk of recurrent infections and autoimmune reactions.

Answer 11

(e.g., in DiGeorge Syndrome)

Question 12

Answer 12

Thymic medulla
Cortext and medulla
Site of T lymp activation

Question 13

Answer 13

Thymic(hassall’s) Corpuscles
Only in the thymic medulla, epthielia cells arranged in a layers.
HIGH MAG

Question 14

White
Yellow
Blue

Answer 14

White: Thymocytes(small nuclei)
Yellow: Epithelial Cells(Euchromatic nuc)
Blue: Macrophages used to phagocytose rejected thymocytes.

Question 15

Answer 15

Lymph node

Question 16

Answer 16

Tonsil(MALT)

Question 17

Answer 17

Spleen

Question 18

Answer 18

BALT(Bronchus)

Question 19

Answer 19

APPY GALT(Gut)

Question 20

Answer 20

GALT

Question 21

Answer 21

Oral Cavity: infolding of strafified squamous epithelium

Question 22

Answer 22

Lymph node has a distinct cortex and medulla

Cortex= bcell
Medulla= tcell

Question 23

Answer 23

Superfical Cortex - nodules present
deep cortex - no nodules

Question 24

Answer 24

Medullary cord house the plasma and APC cell

Question 25

Answer 25

Red=acidophillic(pink)
Used for RBC
White pulp=basophillic(blue)
Immune

Spleen