Lecture 13 Flashcards
Best way to measure muscle mass - which technique
Cross sectional cut of the thigh
Which muscles can change faster? Big or small muscles?
Bigger muscles change faster
Why does muscle mass matter? (7 factors)
Strength and functionality
Metabolism
Bone health
Insulin sensitivity
Functional independence
Hormonal balance
Longetivity
Why does having more muscle affect the risk of diabetes?
Having more muscle = reducing the risk because more muscles can utilize glucose
Why does muscle mass impact the functionality in older adult?
Reduces the risk of fall (more stability)
How does muscle mass affect bone density?
Increase in mechanical stress (pulling on the bone from the muscle) done through physical activity
What is cachexia?
Loss of body weight and muscle mass, and weakness.
Rate of cachexia after the age of 45 years old
0.8
Rate of cachexia after the age of 65 years old
1.5
Can we stop cachexia?
No, maybe slow it down
Muscle mass matters… (6 things)
- Reduced severity of Alzheimer’s disease
- Reduced ventilation time and length of stay in ICU
- Reduced risk of complications for patients after surgery
- Better response to cancer tx
- Better respiratory parameters in COPD
- Higher survival rate for patients after trauma
True or false? Muscle hypertrophy is much faster than muscle atrophy?
FALSE
Takes 3 days of bedrest to start loosing muscle mass vs 6-8 weeks to gain
How much time does it take to start loosing muscle mass if you are in bedrest?
3 days
Relationship between MPB and MPS
Inverse
What is MPB
Muscle protein breakdown
What is MPS
Muscle protein synthesis
Skeletal muscle serves many purposes: name 6
- Producing movement
- Sustaining body posture and position
- Maintaining body temperature
- Storing nutrients
- Stabilizing joints
Skeletal muscle is to contract in response to what
To contract in response to a stimulus
Most skeletal muscle contraction are under _____ control
Voluntary control, receiving neural inputs allowing conscious control of muscles
What happens when you roll your ankle because you thought there were only 3 steps in the stairs so you miss the last one?
Need to send a specific muscle to contract the muscle so if there is none, you fall