Lecture 12 - Oral Manifestations of Dermatologic Diseases Flashcards
Lichenoid
Idiopathic Lichen Planus Lichenoid drug eruption Lupus Erythematous Graft v. Host Disease Hepatitis C
Autoimmune Disease
Pemphigus vulgaris
Paraneoplastic pemphigus
Mucous membrane pemphigoid
Immune-Mediated
Erythema multiforme
Stevens-Johnson Syndrome
Toxic Epidermal Necrolysis
Idiopathic Lichen Planus
Reticular
- common
- lacy, white striations
Erythematous or Ulcerative
- less common
- desquamative gingivitis
Drug Rxn, Tx w/ topical corticosteroids
Desquamative Gingivitis
Peeling away of gingiva
Manifestation of lichen planus, hypersensitivity rxn, or pemphigoid
Sensitive to spicy food
Systemic Lupus Erythematous
Female, 30s
Lichenoid lesions of palate, buccal mucosa, or gingiva
Ulceration, pain, erythema, hyperkeratosis
Renal Failure
Chronic Cutaneous Lupus
Few systemic symptoms
Oral lesions
Lichen planus, fine white striae
Sensitive to acidic or salty foods
Graft v. Host Disease
Oral lesions in 33-75% of acute and 80% of chronic cases
White striae
Diffuse white papules on tongue, buccal, labial mucosa
Ulcers
Xerostomia
Pemphigus Vulgaris
Fatal
50yo
Antibody to desmosomes
Bullae
Intraepithelial separation above basal level
Paraneoplastic Pemphigus
Underlying neoplasm (CLL, Lymphoma, Thyoma)
Skin and oral bullae
Lip crusties
Eye scarring
Mucous Membrane Pemphigoid
Female, 50-60yo
Antibodies to hemidesmosomes
Ocular lesions
Intraepithelial separation below basal level
Erythema Multiforme
Secondary to infection (HSV or mycoplasma pneumoniae)
Male, 20-40yo
Hemorrhagic lip crusties, shallow ulceration
Perimeter of tongue
gingiva and hard palate spared
Stevens Johnson Syndrome
Drug rxn
head and trunk
oral, genital, and ocular lesions
Toxic Epidermal Necrolysis
> 30% surface area involvement
Diffuse sloughing of skin & mucosal surfaces
Dehydration & infection
35% mortality rate
