Lecture 11: Gene Regulation Flashcards

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1
Q

___ genes were one of the very first genes discovered, which regulate proteins associated with early eye and brain development.

A

PAX 6

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2
Q

___ genes are important for the early embryo for the development of proteins needed to define basic body parts, body regions, or body segments.

A

Master

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3
Q

___ genes help define and develop specific body segments after they are formed.

A

Homeotic

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4
Q

___ genes, when mutated, has been shown to cause fruit fly antennae to become functional legs.

A

Homeobox

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5
Q

What is the LAC Operon?

A

An operon or a group of genes with a single promoter that encodes genes for the transport and metabolism of lactose

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6
Q

When RNA polymerase is recruited to the DNA, it first attaches to the ___ region. This is the “binding site” for RNA polymerase.

A

Promoter Region

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7
Q

The repressor protein attaches to the ____.

A

Operator Region

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8
Q

Collectively, what do the “structural genes” do?

A

Break apart lactose

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9
Q

What do the “regulator genes” do?

A

Produce repressor proteins

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10
Q

Does lactose stimulate the production of proteins to break them down?

A

No, it prevents the inhibition of proteins to break them down

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11
Q

When lactose is present, it attaches to the ____.

A

Repressor Protein

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12
Q

Lactose acts as a ____ inhibitor to the repressor protein.

A

Non-competitive

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13
Q

A buildup of phenylalanine is called ___

A

Phenylketonurea

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14
Q

Phenylalanine is normally converted to ___

A

Tyrosine

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15
Q

What group of macromolecules does galactose belong?

A

Carbohydrate

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16
Q

The enzyme ___ normally metabolizes and breaks down galactose.

A

Galt

17
Q

A mutated GALT enzyme is the cause of the condition called ___

A

Galactosemia

18
Q

Where is hemoglobin found in your body?

A

Red blood cells

19
Q

Hemoglobin is a protein that ____.

A

Carries oxygen and carbon dioxide

20
Q

The hemoglobin molecule is made of ____ (number) of monomers, forming a quaternary shape.

A

Four

21
Q

In the second polypeptide chain, if the 6th codon (that codes for glutamic) acid is changed to code for ____, it results in a genetic disease.

A

Valine

22
Q

When the hemoglobin molecule is mutated, the genetic disease called ____ can occur.

A

Sickle-cell anemia