Lecture 11: Abdominal Pain Readings Flashcards
When does an AAA require repair?
- Symptomatic
- >= 5.0cm
Classic presentation of ruptured AAA
- Older male smoker
- hx of atherosclerosis
- Sudden back/abd pain, hypotension, pulsatile abd mass
- Onset of pain is both severe and abrupt.
What hx might predispose aortoenteric fistulas?
Prior aortic grafting
Duodenum MC location
When do you really start monitoring an AAA?
Once it hits 3cm, refer to vascular to monitor
What is the MC initial misdiagnosis for an AAA?
Renal colic
What bedside study is helpful in identifying unclear AAA?
Bedside abdominal US
Measures diameter only!
You really need a CTA
Goal SBP for ruptured AAA
90 SBP
What two layers is blood pouring between for an aortic dissection?
Between the intima and adventitia
Classic demographic of Aortic Dissection
- Older male (>50y) using cocaine
- Hx of HTN
- CT disorders (EDS, Marfan’s, or CHD)
Stanford classification and Debakey of aortic dissections
- Stanford is just Type A = Ascending, B = descending
- DeBakey is type 1 = both, type 2 = ascending, type 3 = descending.
What kind of murmur can be heard during aortic dissection?
Diastolic murmur of aortic insufficiency
MC XR findings for aortic dissection
- Abnormal aortic contour + widening of mediastinum
- Tracheal deviation
- Displacement of aortic intimal calcifications
Imaging modality of choice for aortic dissection
CT Scan with IV contrast (altho im pretty sure its CTA)
Alternate is TEE
How do we manage HTN initially in aortic dissection?
- Esmolol
- Labetolol
Goals: 100-120 SBP, 60-70 HR
If SBP of 100-120 is not met after BB usage in aortic dissection, what can we use?
- Nitroprusside
- Nicardipine
In elderly patients, what hx is important besides the abdominal pain hx?
- Hx of MI
- Dysrhythmias
- Coagulopathies
- Vasculopathies
What is the most important part in the physical exam for abdominal pain?
Palpation
What combination is pretty confirmatory for peritonitis?
- Rigidity
- Referred tenderness
- Cough pain
Also use a Carnett test!
Who gets a pelvic exam in evaluation for abdominal pain?
Any post-pubertal female
In a patient older than 50 showing pain out of proportion to the PE, what is an important DDx to consider?
Mesenteric ischemia
Generally, what does plain XR look for in abdominal pain?
- Obstruction
- Perforation
- Free air
Generally, what does US look for in abdominal pain?
- Stones
- Fluid build-up
- AAA
What is the MC need for abdominal pain that needs resuscitation?
IV fluids (NS/LR)
If we accidentaly give too much morphine, how can we undo it?
Naloxone
Generally, what is considered an “acute/surgical abdomen”?
- Pain
- Guarding (involuntary)
- Rebound
Overall, what is the purpose of analgesics and antiemetics for abdominal pain?
Making it easier to workup/evaluate the patient
So you can get their PE findings more accurately.
Top 2 RFs for PUD
- H. Pylori infection
- NSAIDs (chronic)
Classic description of PUD
- Burning epigastric pain
- Relieved by ingestion of food/milk/anatacids
- Recurrent pain that awakens patient up at NIGHT
What change in someone with PUD suggests perforation?
Abrupt onset of severe pain
What epigastric pain description is most indicative of GERD?
- Radiating into chest
- Belching
In what population is epigastric pain more suspicious and what condition?
Elderly; it could be an atypical MI
Gold standard for diagnosis of PUD
EGD showing an ulcer
Definitive diagnosis of PUD
What are the alarm features for possible cancer with upper GI bleeding?
- Older than 55
- Unexplained Wt loss
- Early satiety/anorexia
- Persistent vomiting
- Dysphagia
- Anemia
- Abd Mass
- Jaundice
Main 3 drugs used to aid in acid decrease for PUD?
- PPIs (-prazoles)
- H2RAs (-tidines)
- Liquid Antacids
Triple therapy H. pylori eradication
- Omeprazole 20mg BID
- Amoxicillin 1g BID
- Clarithomycin 500mg BID
Quadruple eradication therapy H. pylori
- PPI BID
- Metronidazole QID
- Tetracycline QID
- Bismuth QID
How long is eradication therapy for H. pylori?
14 days
How do you definitively diagnose PUD?
Endoscopy
Anyone with a presumptive dx or alarm features
Mainstay of tx for stable, uncomplicated PUD?
PPI or H2RA w/ liquid antacid for breakthrough.
2 MCC of Acute pancreatitis
- Cholelithiasis
- Alcohol Abuse
What condition can result in secondary pancreatitis?
Severe hyperlipidemia
Classic acute pancreatitis
- Mid-epigastric pain that is constant
- Radiates to the back
- Worse when supine
What 3 features of the H&P make acute pancreatitis highly likely?
2 out of 3 is very sus
- H&P consistent with acute pancreatitis
- Lipase or amylase 2-3x ULN
- Imaging showing pancreatic inflammation
Preferred lab test for acute pancreatitis
Lipase
What CBC findings are seen in acute pancreatitis?
Leukocytosis or anemia
What lab findings suggest complicated pancreatitis?
- Persistent hypocalcemia < 7
- Hypoxia
- Increasing BUN
- Metabolic acidosis
Preferred imaging modality for acute pancreatitis
Abdominal CT
Initial tx of pancreatitis
Fluids
When are ABX used for pancreatitis and what are they?
Infected pseudocyst, abscess, infected fluid
- Imipenem-cilastatin
- Meropenem
- Cipro + metro
What procedure is used for Gallstone pancreatitis?
ERCP + Sphincterotomy
4 MC biliary tract emergencies caused by gallstones
- Biliary colic
- Cholecystitis
- Gallstone pancreatitis
- Ascending cholangitis
Top RFs for gallstones
- Old
- Female
- Obese
- Rapid wt loss/fasting
- Asians
- Sickle cell disease
Classic description of biliary colic
- RUQ
- Colicky to constant pain
- N/V
- Episodic
- Referred pain to R shoulder or left upper back
If biliary colic pain persists longer than 5 hours, what is it probably?
Acute cholecystitis
Most sensitive physical test for cholecystitis
Murphy’s sign
Which version of cholecystitis has the worst prognosis?
Acalculous cholecystitis
DM, elderly, trauma, post-sx
What is ascending cholangitis?
- Complete biliary obstruction
- Bacterial superinfection
- Charcot triad may be present: Fever, Jaundice, RUQ Pain
Emergency!!!
Elevation of what 2 labs may suggest choledocholithiasis or ascending cholangitis?
- Serum bilirubin
- ALP (stasis)
Initial imaging modality for suspected biliary colic or cholecystitis?
US of the hepatobiliary tract
Can also do sonographic Murphy’s
Chole = murphy’s and murphy’s has a sonographic version so US is preferred imaging
What US finding suggests choledocholithiasis?
Bile duct diameter > 5cm
If US seems inconclusive for suspected cholecystitis, what is the 2nd imaging modality we should consider?
Radionuclide scan (HIDA scan)
First step in managing cholecystitis
Fluids
What is the empiric ABX for uncomplicated cholecystitis?
Anyone with suspected chole gets this
Cefotaxime/ceftriaxone + Metronidazole
What is the empiric ABX for Complicated cholecystitis or ascending cholangitis?
- Ampicillin
- Gentamicin
- Clindamycin
Triple coverage
Clint the gentle amp
Which chole conditions require ERCP + Sphincterotomy?
- Choledocholithiasis
- Gallstone pancreatitis
- Ascending Cholangitis
Other conditions need surgery
When can you discharge someone with uncomplicated biliary colic?
- Symptoms abate with tx in 4-6 hrs
- PO tolerable
Most reliable symptom of appendicitis
Abdominal pain (Classically in the RLQ at Mcburney’s)
Where exactly is McBurney’s point?
2/3 Between Umbilicus and ASIS
More laterally
What 3 physical exam tests can be done to check for appendicitis?
- Rovsing’s (roving from LLQ to RLQ)
- Psoas (Left lateral decubitus, Stretch SOAS)
- Obturator (Flex R Hip + Knee + Internal rotation)
Why does appendicitis pain location vary?
Your appendix can move around (pelvic, retrocecal, etc)
Although a late finding, what is the most useful sign suggestive of appendicitis?
Fever
Rebound tenderness, then pain localizing to RLQ.
Highest sensitivity S/S for appendicitis
- Fever
- RLQ pain
- Pain before vomiting
- Absence of prior similar pain
What transition in pain is considered highly predictive of appendicitis?
Migration to the RLQ
Starts more diffusely
What is the imaging study of choice for establishing the diagnosis of appendicitis?
CT (non-con is pretty accurate)
DO NOT USE RADIOGRAPHS
Thin patients might be false negative
In children and pregnant patient, we prefer a different imaging modality over CT for acute appendicitis. What is it?
Graded compression US
Which imaging modality works for appendicitis and is not reliant on operator skill?
MRI
No ionizing radiation, no contrast needed
What is the MC surgical emergency in pregnant patients?
Acute appendicitis
Mainstay of tx for acute appendicitis
Appendectomy
Empiric abx prior to appendectomy
- PiptaZo (Zosyn)
- AmpSul (UnaSyn)
What populations are you probably not sure of acute appendicitis in?
- Pediatric
- Geriatric
- Pregnant
- Immunocompromised
Admit for serial exams + monitoring
Classic diverticulitis
- LLQ pain (Steady & deep)
- Fever
- Leukocytosis
What RFs cause diverticulitis to present in the R quadrant?
- Redundant sigmoid
- Asian
- Right-sided disease
How is diverticulitis diagnosed?
Clinically/Imaging
Only need imaging if fail conservative tx or unclear or SUS
Generally, only a person with hx of diverticulitis does not need imaging if presentation is similar to previous.
Any systemic S/S or inability to undergo conservative tx = CT abd pelvis w/ IV con
Preferred imaging modality to evaluate diverticulitis (r/o ddx)
CT w/ con (extremely high spec and sens)
ABX of uncomplicated diverticulitis (oral, outpatient)
- Metronidazole plus
- Cipro or levofloxacin or Bactrim
Augmentin or Moxifloxacin alternate
Cipro + Metro
ABX of moderate diverticulitis (inpatient, IV)
- Metro plus
- Cipro or levofloxacin or aztreonam or rocephin
Cipro + metro, just switch to IV for Inpatient
ABX for severe diverticulitis
- Ampicillin plus
- Metronidazole plus
- Cipro or amikacin/gentamicin/tobramycin
Cipro + Metro + Amp because you need to amplify the regimen for severe from inpatient.
How soon do you f/u with GI if you’re being treated for diverticulitis OP?
6 weeks if you show improvement
I think for a colonoscopy
Top RFs for SBO
- Previous bowel surgery
- Incarcerated hernias
- Inflammatory diseases
Who is sigmoid volvulus MC in?
Elderly taking an anticholinergic
Think benadryl, hydroxyzine, oxybutynin
Who is cecal volvulvus MC in?
Gravid patient
Who is Ogilvie syndrome/intestinal pseudo-obstruction MC in?
Bedridden elderly on anticholinergics or TCAs
Mimics large bowel obstruction
What does bilious vomiting suggest?
Proximal obstruction
What does feculent vomiting suggest?
Distal obstruction
In mechanical SBO, when are high-pitched bowel sounds heard?
Early
How is ileus treated vs SBO?
- Ileus: Observe and hydrate
- SBO: NG tube +/- surgery
Diagnostic imaging modality of choice in the ED for bowel obstruction
CT scan (w/ contrast when possible)
Helps differentiate partial vs complete vs ileus vs strangulated.
If leukocytosis > 20k is noted with bowel obstruction, what are we concerned about?
- Abscess
- Gangrene
- Peritonitis
What does elevated hematocrit suggest for bowel obstruction?
Dehydration
Initial tx for managing bowel obstruction
NG tube
Pre-op abx for mechanical SBO requiring surgery?
- Zosyn
- Tircarcillin-clavulanate (discontinued in the US in 2015)
- Unasyn
- Cefotaxmine/rocephin + clinda/metro/carbapenem
In patients with Ogilvie/pseudo-obstruction, what is the dx and tx?
Colonoscopy
For an unclear bowel obstruction that is non-surgical, what is the mainstay of tx?
- NG Tube
- IV fluids
- Observation