Lecture 10: The heart as a pump Flashcards

1
Q

Describe the phases of the cardiac cycle:

A
Atrial systole
Isovolumetric contraction
Ejection 
- Rapid ejection
- Reduced ejection
Isovolumetric relaxation
Filling
- Rapid filling
- Reduced filling
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2
Q

Upload the wiggers diagram

A

Explain

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3
Q

What is isovolumetric contraction?

A

The phase between start of ventricular systole and the opening of the semilunar valves.

  • Sharp rise in pressure, no change in volume. (Isometric contraction at this stage, isotonic during ejection)
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4
Q

What does the onset of isovolumetric contraction co-incide with?

A
  • Peak of R wave
  • S1
  • Earliest rise in ventricular pressure
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5
Q

What can ventricular ejection be divided into?

A

Early: Rapid ejection phase
Later: Reduced ejection phase

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6
Q

What are the three characteristics of the ejection phase?

A
  • Sharp rise in ventricular and aortic pressure (b/c valves open) -> Terminated at the peak of pressure wave
  • Dec. ventricular volume
  • Inc. aortic blood flow
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7
Q

Describe the reduced ejection phase

A

The flow from the aorta is greater than the flow from the ventricle therefore the pressure in the aorta declines.

  • Reversal of the ventricular-aorta pressure gradient duing continuous LV flow.
  • Decceleration of the flow from the LV into the aorta.
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8
Q

Describe isovolumetric relaxation:

A
  • Closure of aortic valve produces insura (notch) on the P curve (and S2)
  • Period b/w semilunar closure and AV opening
  • Rapid decrease in P w/o change in volume
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9
Q

Describe the rapid filling phase: (passive)

A
  • AV valves open and blood flows into ventricles (pressure gradient)

(reduced filling phase follows (Diastasis)

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10
Q

Describe diastasis: (passive)

A
  • Slow ventricular filling
  • (Follows rapid filling phase)
  • Gradual rise in atrial and venous pressures as volume increases.

(length of passive filling determined by heart rate)

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11
Q

Describe atrial systole:

A
  • Occurs just after P wave
  • Completes ventricular filling
  • Contributes to ventricular filling dependant on HR
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12
Q

What are venous pulse waves?

A

Atrial P waves

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13
Q

Describe the venous pulse waves:

A

a wave - Reterograde pressure pulse in jugular when atria contract

c wave - during early phase of ventricular systole

v wave - gradual pressure increase during reduced ejection and isovolumic relaxation

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14
Q

What does JVP show us?

A

Indirect measure of central venous pressure (venous hypertension)

(raised right atrial pressure results in distension of internal jugular vein)

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15
Q

What are cardiac causes of raised JVP?

A

Right sided HF
Tricuspid regurgitation
Constrictive pericarditis

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16
Q

What is the first heart sound?

A

Beginning of contraction, closure of AV valve, rapid P development, opening of semilunar valves and outflow

17
Q

What is the second heart sound?

A

Tensing of aortic and pulmonary valves and resulting vibrations

18
Q

Ficks and thermodilutiion

A

Grab the questions?

19
Q

add right and left wiggers

A

now

20
Q

What is the equation for total peripheral vascular resistance?

A

P(SA)-P(SV) / Q(flow) = TPVR

21
Q

What is the equation for pulmonary vascular resistance?

A

PVR = P(PA) - P(LA) / Q