Lecture 10- energy production and oxygen consumption

Question 1

What are the 6 steps in the oxygen cascade

Answer 1

1-humidification
2-alveolar gas
3-alveolar-capillary diffusion
4-ventilation-perfusion mismatch and shunt
5-tissue diffusion
6-diffusion within cell

Question 2

does oxygen partial pressure increase or decrease at each part of the cascade

Answer 2

decrease

Question 3

define oxygen consumption

Answer 3

amount of oxygen used by the body in one minute

Question 4

what factor affect oxygen consumption

Answer 4

age, temperature, exercise

Question 5

state 4 physiological responses to anaemia

Answer 5

increased 2,3-DPG shifts Hb curve right
reduced blood flow to non essential organs
increased oxygen extraction from blood
increase in cardiac output

Question 6

define respiratory exchange ratio

Answer 6

ratio of CO2 production to oxygen consumption

Question 7

what is respiratory exchange ratio affected by

Answer 7

acid base balance, hyperventilation, metabolic fuel

Question 8

how is oxygen used when generating energy

Answer 8

oxidative phosphorylation- combines with H+ to produce H2O

Question 9

What are the three causes of cellular hypoxia

Answer 9

anoxic(lack of O2), stagnant(lack of blood supply), anaemic (lack of Hb)