Lecture 1 - Osmosis and Diffusion Flashcards
Define osmosis
Osmosis is the movement of water (the solvent) across a semi-permeable membrane to even the concentration of dissolved particles on either side of the membrane.
*osmosis only cares about the number of particles not their identity
Define diffusion
Diffusion is the movement of particles dissolved (the solute) in a solution to even the distribution of that particle in the solution. Occurs when there is a net flow from region of high concentration to region of low concentration
Hypertonic
Cells lose water by osmosis and shrink in a hypertonic solution (contains a higher concentration of solutes than are present inside the cells)
= SHRINK
State the fluid compartments of the body
- Extra cellular fluid
- plasma fluid
- interstitial fluid
- 20% of total body weight - Intercellular fluid
- 40% of total body weight
Plasma has lots of proteins
Isotonic
Water moves in and out of cell at same rate and cell maintains structure due to equal concentration of water inside and out of cell
Hypotonic
Cells become bloated and possible burst (lyse) due to water coming into cell as concentration of water is greater outside than inside cell
What is the difference between osmolarity and concentration
It is quite clear that molarity measures the number of moles of solute per unit volume of solution, while osmolarity measures the number of osmoles of solute particles per unit volume of solution.
What is the difference between osmolarity and Tonicity?
Osmolality is a property of a particular solution and is independent of any membrane. Tonicity is a property of a solution in reference to a particular membrane.
Define homeostasis
Homeostasis is the maintenance of a stable internal environment notwithstanding changes in the external environment. It is self regulating system
Describe the basic reflexes involved in maintaining homeostasis
Autonomic reflex’s such as heart rate, breathing rate, BP and digestion. Uses both negative feedback and positive feedback loops
Identify the major components of a reflex arc
Receptors, sensory neurons, inter neurons, motor neurons, muscles
Example of endocrine system negative feedback loop
Water levels rise in blood —> osmoreceptors in brain detect —> osmoregulatory centre in hypothalamus—> less ADH is released by pituitary—> water levels decrease
Fick’s law of diffusion
- Thickness of membrane
- Permeability of barrier
- Concentration gradient
- Surface area available