Lecture 1: Intro to Immune Responses Flashcards
First defense level
Physical and chemical
Second defense level
Innate immune response
Third defense level
Adaptive immune response
Orchestrator of adaptive immune response
Lymphocyte
Communicator within innate system
Cytokine
These two use cytokines to regulate intensity of immune response
Macrophages and lymphocytes
Mannose
Prominent feature in bacterial cell walls and metabolism; example of a PAMP
Germ-line derived immune system
Innate immune system
Two types of leucocytes
Neutrophils and macrophages
Role of leucocytes
Detection of PAMPs and DAMPs
Good at phagocytosis
These contrain granules loaded w/ lethal/oxidizing/hydrolytic molecules
Leucocytes
Gateway to immune system
TLRs, present on innate cells
Liver-produced proteins compose this system
Complement system
Two-chain peptides
Cytokines (truuuu)
Sentinel cells of immune system; critical for activation of the adaptive system
Dendritic cells (type of leucocyte)
- Rich in TLRs
- Recognize DAMPs and PAMPs