Functional Lymphoid

Question 1

Purpose of lymphoid tissue

Answer 1

• Support lymphopoiesis (generation of lymphocytes)
• Support development of super diverse repertoire of antigen-specific lymphocytes
• Central and peripheral tolerance
• Sustaining signals for lymphocyte survival

Question 2

Examples of central lymphoid tissue

Answer 2

Bone marrow and thymus

Question 3

Example of peripheral lymphoid tissue

Answer 3

Lymph nodes, spleen, and mucosal associated lymph tissue

Question 4

Responsible for lymphopoieses (Central vs Peripheral)

Answer 4

Central

Question 5

Mixture of B and T cells (Central vs Peripheral)

Answer 5

Peripheral

Question 6

Supports circulating lymphocyte survival (Central vs Peripheral)

Answer 6

Peripheral

Question 7

Activation of naive lymphocytes (Central vs Peripheral)

Answer 7

Peripheral

Question 8

Central tolerance (Central vs Peripheral)

Answer 8

Central

Question 9

Peripheral tolerance (Central vs Peripheral)

Answer 9

Peripheral

Question 10

Contains only immature thymocytes and scattered macrophages

Answer 10

Thymic cortex

Question 11

Site for most T cell development

Answer 11

Thymic cortex

Question 12

Site of entry for T cell progenitors

Answer 12

Corticomedullary junction

Question 13

Network of epithelia where T cell prescursors reside

Answer 13

Thymic cortical stroma

Question 14

Site of RBC destruction

Answer 14

Red pulp (spleen)

Question 15

Site of iron recycling

Answer 15

Red pulp (spleen)

Question 16

Site of immune responses to blood borne pathogens

Answer 16

White pulp (spleen)