[LEC] Granulopoiesis

Question 1

PROGENITOR CELL OF GRANULOCYTES

Answer 1

CFU-G

Question 2

WHAT GRANULOCYTE PRECURSORS ARE FOUND IN THE MITOTIC POOL

Answer 2

MYELOBLAST
PROMYLOCYTE
MYELOCYTE

Question 3

WHAT GRANULOCYTE PRECURSOR CELLS ARE FOUND IN THE STORAGE POOL

Answer 3

METAMYELOCYTE
STAB/BAND CELL

NEUTROPHIL
EOSINOPHIL
BASOPHIL

Question 4

MATURATION ORDER OF GRANULOPOIESIS

Answer 4

CFU-G
MYELOBLAST
PROMYELOCYTE
MYELOCYTE
METAMYELOCYTE
BAND/STAB CELL
NEUTROPHIL/EOSINOPHIL/BASOPHIL

Question 5

GRANULOCYTE PRECURSORS THAT ARE CAPABLE OF DIVIDING

Answer 5

MYELOBLAST
PROMYELOCYTE
MYELOCYTE

Question 6

GRANULOCYTES THAT ARE CAPABLE OF DIVIDING

Answer 6

MYELOBLAST
PROMYELOCYTE
MYELOCYTE

Question 7

GRANULOCYTES INCAPABLE OF DIVIDING

Answer 7

METAMYELOCYTE
BAND/STAB CELL
NEUTROPHIL/EOSINOPHIL/BASOPHIL

Question 8

GRANULES THAT ARE PRODUCED FIRST BUT USED LAST

Answer 8

PRIMARY OR AZUROPHILIC GRANULES

Question 9

GRANULES THAT ARE PRODUCED LAST BUT USED FIRST

Answer 9

TERTIARY GRANULES

Question 10

PRECURSOR CELL THAT PRODUCES PRIMARY GRANULES

Answer 10

PROMYELOCYTE

Question 11

PRECURSOR CELL THAT PRODUCES SECONDARY GRANULES

Answer 11

MYELOCYTE

Question 12

PRECURSOR CELL THAT PRODUCES TERTIARY GRANULES

Answer 12

METAMYELOCYTE

Question 13

PRESENCE OF GRANULES IN THE MYELOBLAST

Answer 13

NONE

Question 14

COLOR OF THE MYELOBLAST’S CYTOPLASM

Answer 14

PALE OR CLEAR BLUE

Question 15

DIAMETER OF THE MYELOBLAST

Answer 15

15 UM

Question 16

WHAT NUCLEAR PRODUCT DOES THE PROMYELOCYTE MAKE

Answer 16

PRIMARY OR AZUROPHILIC GRANULES

Question 17

CHROMATIN BEGINS TO CLUMP IN THIS PRECURSOR CELL

Answer 17

PROMYELOCYTE

Question 18

WHAT NUCLEAR PRODUCT DOES THE MYELOCYTE MAKE

Answer 18

SECONDARY OR SPECIFIC GRANULES

Question 19

PRECURSOR CELL WITH THE D SHAPED NUCLEUS

Answer 19

MYELOCYTE

Question 20

SHAPE OF THE MYELOCYTE’S NUCLEUS

Answer 20

D SHAPED

Question 21

COLOR OF THE MYELOCYTE’S CYTOPLASM

Answer 21

PINK

Question 22

SEEMINGLY HOURGLASS SHAPE

Answer 22

MYELOCYTE

Question 23

LAST CELL CAPABLE OF CELL DIVISION

Answer 23

MYELOCYTE

Question 24

DAWN OF NEUTROPHILIA
-Identify the cell and state the cause

Answer 24

MYELOCYTE
Transition of cytoplasm’s color from blue to pink
Protein production reduces
Basophilia decreases

Question 25

WHAT NUCLEAR PRODUCT DOES THE METAMYELOCYTE MAKE

Answer 25

TERTIARY GRANULES

Question 26

SHAPE OF THE METAMYELOCYTE NUCLEUS

Answer 26

KIDNEY SHPE Indented nucleus Not more than half of the nucleus

Question 27

CELL WITH THE KIDNEY SHAPED NUCLEUS

Answer 27

METAMYELOCYTE

Question 28

CELL WITH THE FIRST NUCLEAR CHANGE

Answer 28

METAMYELOCYTE

Question 29

INDENTATION OF THE NUCLEUS IS MORE THAN HALF OF IT IN THIS CELL

Answer 29

STAB OR BAND CELL

Question 30

HAS A C SHAPED NUCLEUS

Answer 30

BAND OR STAB CELL

Question 31

IMMATURE GRANULOCYTE ALLOWED TO ENTER PERIPHERAL CIRCULATION

Answer 31

STAB OR BAND CELL

Question 32

[TRUE OR FALSE] THE PRESENCE OF THE BAND CELL IN CIRCULATION IS OF CLINICAL SIGNIFICANCE

Answer 32

FALSE

Question 33

RATIO OF SEGMENTERS TO PRECURSORS

Answer 33

1:16 1 SEGEMENTED @ PC 16 PRECURSORS @ BM

Question 34

WHERE ARE SEGMENTERS FOUND IN

Answer 34

PERIPHERAL CIRCULATION

Question 35

WHERE ARE PRECURSORS FOUND IN

Answer 35

BONE MARROW

Question 36

PERIOD OF TIME IN BETWEEN TRANSITIONS FROM MYELOCYTE TO SEGMENTER TO STORAGE POOL

Answer 36

MYELOCYTE -14 DAYS- SEGMENTER - 6-7 DAYS- STORAGE POOL

Question 37

DESCRIBE THE TRAVEL MECHANISM OF NEUTROPHILS

Answer 37

NEUTROPHILS ATTACH TO THE ENDOTHELIUM AND SQUEEZE OUT VIA DIAPEDESIS CHEMOTAXINS HELP THEM TRAVEL DIRECTLY TO THE SITE OF CELL DESTRUCTION

Question 38

ENUMERATE AND DESCRIBE THE PHAGOCYTOSIS PROCESS

Answer 38

RECOGNITION and ATTACHMENT Determine self from non self INGESTION Formation of the phagosome KILLING AND DESTRUCTION

Question 39

ENUMERATE THE TWO KINDS OF NEUTROPHIL KILLING MECHANISMS

Answer 39

O2 DEPENDENT Granules release superoxides O2 INDEPENDENT Changes in pH occur From alkaline to neutral

Question 40

KILLING MECHANISM THAT USESS SUPEROXIDES RELEASED BY GRANULES

Answer 40

O2 DEPENDENT

Question 41

KILLING MECHANISM THAT CHANGES PH

Answer 41

O2 INDEPENDENT

Question 42

THE FUSION OF A NEUTROPHIL AND AN INGESTED BODY RESULTS IN WHAT

Answer 42

PHAGOSOME

Question 43

ORDER OF GRANULE USAGE

Answer 43

TERTIARY — SECONDARY — PRIMARY

Question 44

PROGENITOR CELL OF EOSINPHILS

Answer 44

CFU-EO

Question 45

COLOR OF THE INITIAL GRANULES OF THE EOSINOPHIL

Answer 45

OLIVE GREEN

Question 46

COLOR OF THE MATURE GRANULES OF THE EOSINOPHIL

Answer 46

DEEP ORANGE TO RED

Question 47

CHARACTERISTIC APPEARANCE OF THE EOSINOPHIL NUCLEUS

Answer 47

CLASSIC HEADPHONE SHAPE

Question 48

CORE PROTEINS OF THE EOSINOPHIL

Answer 48

MAJOR BASIC PROTEIN

Question 49

PH OF THE MBP

Answer 49

ALKALINE

Question 50

STRAINING PROPERTY OF THE MBP

Answer 50

DEEP ORANGE TO RED

Question 51

GENERAL FUNCTION OF THE EOSINOPHIL

Answer 51

DAMPEN OR WEAKEN THE IMMUNE RESPONSE Counters the enhancing effect of basophils

Question 52

AN INCREASE OF EOSINOPHILS CAN BE SEEN IN WHAT CLINICAL CONDITIONS

Answer 52

ACTIVE PARASITISM

Question 53

FOUR MAIN FUNCTIONS OF EOSINOPHILS

Answer 53

DEGRANULATION Directly kill the organism Release granules Mediate basophil function REGULATION OF IMMUNE RESPONSE Work with APCs INDICATORS OF PARASITIC INFECTIONS Major basic proteins battle helminths HALLMARK OF ALLERGIC REACTIONS

Question 54

PREFERRED SPECIMEN FOR THE DETECTION OF CHARCOT LEYDEN CRYSTALS

Answer 54

SPUTUM

Question 55

HALLMARK OF RESPIRATORY CONDITIONS

Answer 55

CHARCOT LEYDEN CRYSTALS

Question 56

CYTOKINE THAT HELPS REPAIR DAMAGED TISSUE

Answer 56

FIBROGENIC DERIVED GROWTH FACTOR

Question 57

PROGENITOR CELL OF BASOPHILS

Answer 57

CFU-BASO

Question 58

GROWTH FACTOR THAT CONVERTS EOSINOPHILS TO BASOPHILS

Answer 58

TGF-Beta Transforming Growth Factor - Beta

Question 59

CYTOKINE THAT EXERT A POSITIVE INFLUENCE ON BASOPHILS

Answer 59

IL-3 IL-5

Question 60

SOLUBLE PROTEINS THAT HAVE DIRECT AND INDIRECT EFFECTS OF HEMATOPOIETIC CELLS

Answer 60

CYTOKINES

Question 61

CELL WITH GRANULES THAT OBSCURE ALMOST THE WHOLE CELL

Answer 61

BASOPHILS

Question 62

GRANULES THAT FORM IN THE METAMYELOCYTE STAGE

Answer 62

METACHROMATIC GRANULES Making it a TERTIARY granules

Question 63

AZUROPHILIC GRANULES OF THE BASOPHILS

Answer 63

METACHROMATIC GRANULES

Question 64

GRANULES THAT CHANGE COLORS AT DIFFERENT LIGHT INTENSITIES

Answer 64

METACHROMATIC

Question 65

SUBSTANCE BASOPHILS RELEASE TO INCREASE ALLERGIC REACTIONS

Answer 65

HISTAMINE

Question 66

SUBSTANCE BASOPHILS RELEASE TO PREVENT BLOOD FROM CLOTTING

Answer 66

HEPARIN

Question 67

FUNCTIONS OF THE BASOPHIL

Answer 67

RESPOND TO ADRENAL CORTICOSTEROIDS IMMEDIATE AND DELAYED HYPERSENSITIVITY REACTIONS RELEASE CYTOKINES INDUCE THE SYNTHESIS OF IGE ANGIOGENESIS CONTROL HELMINTH INFECTIONS

Question 68

WHAT CELL IS THE MOST EFFICIENT AT COMBATING HELMINTH INFECTIONS

Answer 68

EOSINOPHILS

Question 69

REPAIRING OR FORMATION OF BLOOD VESSELS IS TERMED AS

Answer 69

ANGIOGENESIS

Question 70

IMMUNOGLOBULIN THAT INCREASES DUE TO BASOPHILS

Answer 70

IgE

Question 71

[FUNCTION OF WHAT CELL] PHAGOCYTOSIS

Answer 71

NEUTROPHIL

Question 72

[FUNCTION OF WHAT CELL] REGULATION OF THE IMMUNE RESPONSE WITH APCs

Answer 72

EOSINOPHILS

Question 73

[FUNCTION OF WHAT CELL] INDICATOR OF PARASITIC INFECTIONS

Answer 73

EOSINOPHILS

Question 74

[FUNCTION OF WHAT CELL] HALLMARK OF ALLERGIC REACTIONS

Answer 74

EOSINOPHILS

Question 75

[FUNCTION OF WHAT CELL] RESPOND TO ADRENAL CORTICOSTEROIDS

Answer 75

BASOPHILS

Question 76

[FUNCTION OF WHAT CELL] IMMEDIATE AND DELAYED HYPERSENSITIVITY REACTIONS

Answer 76

BASOPHILS

Question 77

[FUNCTION OF WHAT CELL] RELEASE OF CYTOKINES

Answer 77

BASOPHILS

Question 78

[FUNCTION OF WHAT CELL] INDUCES THE SYNTHESIS OF IgE

Answer 78

BASOPHILS

Question 79

[FUNCTION OF WHAT CELL] ANGIOGENESIS

Answer 79

BASOPHILS

Question 80

[FUNCTION OF WHAT CELL] CONTROL HELMINTH INFECTIONS

Answer 80

MAINLY EOSINOPHILS BASOPHILS

Question 81

CELL THAT RESEMBLES BASOPHILS

Answer 81

MAST CELLS