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HEMATOLOGY > [LEC] Agranulocytes > Flashcards

[LEC] Agranulocytes Flashcards

1
Q

MATURATION SEQUENCE OF MONOCYTES

A

CFU-M
MONOBLAST
PROMONOCYTE
MONOCYTE
MACROPHAGE

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2
Q

EARLIEST RECOGNIZABLE MONOCYTE PRECURSOR CELL

A

PROMONOCYTE

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3
Q

CELL WITH THE “GROUND GLASS” CYTOPLASMIC APPEARANCE

A

PROMONOCYTE
MONOCYTE

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4
Q

CELL WITH VACUOLES IN THE CYTOPLASM

A

MONOCYTE

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5
Q

NUCLEAR MATERIAL IN THIS CELL IS “LACEY”

A

MONOCYTE

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6
Q

MONOCYTE CAN BE CONFUSED AS WHAT CELL AND WHY

A

BAND CELL
DUE TO C SHAPED NUCLEUS

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7
Q

NUCLEUS SHAPE OF THE MONOCYTE

A

C SHAPED

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8
Q

FUNCTIONS OF THE MONOCYTE

A

INNATE IMMUNITY
Active elimination of pathogens

ADAPTIVE IMMUNITY
Most potent APCs

HOUSE KEEPING
Continuous ingestion of bodies

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9
Q

SCAVENGER CELLS

A

MONOCYTES

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10
Q

PROGENITOR CELL OF MONOCYTES

A

CFU-M

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11
Q

PROGENITOR CELLS OF THE LYMPHOCYTES

A

CFU-L

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12
Q

MACROPHAGE OF THE BRAIN

A

DENDRITIC CELLS

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13
Q

MACROPHAGE OF THE LIVER

A

KUPFFER CELLS

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14
Q

MACROPHAGE OF THE LUNGS

A

ALVEOLAR MACROPHAGES

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15
Q

MACROPHAGE OF THE SPLEEN

A

RED PULP MACROPHAGE

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16
Q

MACROPHAGE OF THE SKIN

A

LANGERHANS CELLS

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17
Q

MACROPHAGE OF THE HEART

A

CCR2 CELLS

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18
Q

MACROPHAGE OF THE KIDNEY

A

RENAL MACROPHAGES

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19
Q

MACROPHAGE OF THE BLOOD

A

MONOCYTE

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20
Q

CELL MATURATION SEQUENCE OF LYMPHOCYTES

A

LYMPHOBLAST
PROLYMPHOBLAST
PRELYMPHOBLAST
IMMATURE LYMPHOCYTE
MATURE LYMPHOCYTE
— B LYMPHOCYTE —> PLASMA CELL
— T LYMPHOCYTE

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21
Q

LYMPHOCYTE GROUPS

A

T AND B CELLS
NK CELLS

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22
Q

PLAYERS IN THE ADAPTIVE IMMUNITY

A

T AND B CELLS

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23
Q

KILL PATHOGENS REGARDLESS OF WHAT IT IS

A

NK CELLS

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24
Q

CELL THAT PRODUCES ANTIBODIES

A

PLASMA CELLS

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25
Q

PHASES OF LYMPHOCYTE DEVELOPMENT

A

ANTIGEN INDEPENDENT
ANTIGEN DEPENDENT

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26
Q

ANTIGEN INDEPENDENT LYMPHOCYTES

A

CELLS IN THE BM
CFU-L TO IMMATURE LYMPHOCYTES

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27
Q

[PHASE OF DEVELOPMENT]
CELLS THAT ARE IN THE BONE MARROW

A

AG INDEPENDENT

28
Q

[PHASE OF DEVELOPMENT]
CELL NEEDS TO BE EXPOSED TO THE AG

A

AG DEPENDENT

29
Q

[PHASE OF DEVELOPMENT]
CELL TRANSITIONS FROM IMMATURE TO MATURE

A

AG DEPENDENT

30
Q

[PHASE OF DEVELOPMENT]
MATURATION IS IN THE SECONDARY LYMPHOID ORGANS

A

ANTIGEN DEPENDENT

31
Q

MATURATION SEQUENCE OF THE B LYMPHOCYTE

A

CFU-L
PRO-B
PRE-B
IMMATURE OR NAIVE
MATURE
-
PLASMA CELL

32
Q

IMMUNOGLOBULINS PRESENT DURING B CELL MATURATION

33
Q

LINEAGE ASSOCIATED MARKERS OF B LYMPHOCYTES

A

HLA-DR
TdT (Terminal deoxynucleotidyl transferase)

34
Q

MARKERS PRESENT IN PRO-B

35
Q

MARKERS PRESENT IN PRE-B

36
Q

MARKERS PRESENT IN CFU-L

37
Q

MARKERS PRESENT IN PRE-B

38
Q

IN WHAT CELL IS CALLA DETECTED IN

39
Q

MATURE CELLS CONTAIN WHAT MARKERS

A

NO MARKERS

NO CALLA
NO TDT

40
Q

CALLA MEANING

A

COMMON ACUTE LYMPHOCYTIC LEUKEMIA ANTIGEN

41
Q

LYMPHOCYTE THAT LEAVES THE BM TO MATURE IN SECONDARY LYMPHATIC ORGANS

A

IMMATURE LYMPHOCYTE
NAIVE LYMPHOCYTE
HEMATOGONES

42
Q

CLINICAL CONDITION OF CALLA AND TDT PRESENT IN MATURE CELLS

43
Q

OTHER TERMS FOR IMMATURE B LYMPHOCYTE

A

NAIVE LYMPHOCYTE
HEMATOGONES

44
Q

DIAPEDESIS IS MEDIATED BY

A

INTEGRIN
SELECTIN

45
Q

SYNTHESIZES NITRIC OXIDE

46
Q

FIRST CELL TO MANIFEST SURFACE IMMUNOGLOBULINS

A

IMMATURE
IGG, IGM

47
Q

BLASTOGENESIS

A

MATURE LYMPHOCYTES IN THE SECONDARY LYMPH ORGANS

48
Q

LYMPHOPOIESIS

A

IMMATURE LYMPHOCYTES
BONE MARROW

49
Q

ENUMERATE THE ACTIVITY OF SECONDARY LYMPHOID ORGANS

A

AG INITIATES THE ACTIVITY OF IMMATURE B CELL
B CELL IS EXPOSED TO AG
B CELL MATURES INTO MEMORY AND PLASMA CELLS

50
Q

EFFECT OF BLASTOGENESIS ON T LYMPHOCYTES

A

CREATION OF ATYPICAL OR REACTIVE LYMPHOCYTES

51
Q

LARGE GRANULAR LYMPHOCYTE

52
Q

HAS PRONOUNCED GRANULES

53
Q

CELL THAT IS LARGER THAN LYMPHOCYTES

54
Q

[LYMPHOCYTE MARKERS]
T LYMPHOCYTE

55
Q

[LYMPHOCYTE MARKERS]
ATTACKS INTRACELLULAR PATHOGEN

56
Q

[LYMPHOCYTE MARKERS]
ATTACKS EXTRACELLULAR PATHOGEN

A

TH2 — helminths, asthma
TH17 —bacteria. fungi

57
Q

[LYMPHOCYTE MARKERS]
EXTRACELLULAR BACTERIA OF FUNGI

58
Q

[LYMPHOCYTE MARKERS]
MAINTAINS SELF TOLERANCE BY IMMUNE REGULATION

59
Q

[LYMPHOCYTE MARKERS]
KILLS TARGET CELLS, CYTOTOXIC T CELLS

60
Q

CELL THAT KILLS WITHOUT PRIPR SENSITIZATION

61
Q

MATURATION SEQUENCE OF MEGAKARYOCYTES

A

CFU-MEG E
BFU-MEG
CFU-MEG
LD-CFU-MEG
MK-1 (Megakaryoblast)
MK-2 (Promegakaryocyte)
MK-3 (Mature Megakaryocyte)

62
Q

MEGAKARYOCYTE PRECURSOR THAT NO LONGER DIVIDES

A

LD-CFU-MEG

63
Q

DIVISION OF NUCLEAR MATERIAL

A

ENDOMITOSIS

64
Q

CELL THAT PERFORMS ENDOMITOSIS

A

MEGAKARYOCYTE

65
Q

MEGAKARYOCYTE PRECURSOS THAT SHEDS PLATELETS

HEMATOLOGY (13 decks)

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