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HEMATOLOGY > [LAB] Dyshemoglobin > Flashcards

[LAB] Dyshemoglobin Flashcards

1
Q

[TRUE OR FALSE]
HEMOGLOBIN CARRIES OXYGEN FROM THE TISSUES TO THE LUNGS

A

FALSE
IT CARRIES O2 FROM THE LUNGS TO THE TISSUES

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2
Q

TRUE OR FALSE
HEMOGLOBIN CARRIES CARBON DIOXIDE FROM THE TISSUES TO THE LUNGS FOR EXHALATION

A

TRUE

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3
Q

WHAT PROTEIN REGULATES VASCULAR TONE

A

HEMOGLOBIN

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4
Q

HOW DOES HEMOGLOBIN CONTRIBUTE TO ACID-BASE BALANCE

A

THROUGH BINDING AND RELEASING HYDROGEN IONS

TRANSPORTING NITRIC OXIDE

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5
Q

IN WHAT CELLS DOES HEMOGLOBIN SYNTHESIS OCCUR IN

A

RETICULOCYTES
IMMATURE NUCLEATED RBCs

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6
Q

PREDOMINANT HEME (PORPHYRIN) PRODUCERS

A

RED BONE MARROW
LIVER

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7
Q

WHERE IS EXCESS IRON STORED

A

TISSUES
BODY ORGANS (Liver, Heart, Pancreas)

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8
Q

IRON TRANSPORT PROTEIN

A

TRANSFERRIN

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9
Q

MAJOR IRON STORAGE FORM

A

FERRITIN

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10
Q

WATER INSOLUBLE IRON IN STORAGE FORM

A

HEMOSIDERIN

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11
Q

RED CONJUGATED PROTEIN PRESENT IN RBCs

A

HEMOGLOBIN

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12
Q

PERCENTAGE OF RBC MASS HEMOGLOBIN TAKES UP

A

28%

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13
Q

VOLUME OF OXYGEN CONTENT IN GLOBIN

A

1.34 mL

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14
Q

1 GLOBIN CONSISTS OF HOW MANY HEME MOLECULES

A

4 HEME MOLECULES

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15
Q

NUMBER OF IRON ATOMS IN THE FERROUS STATE OF HEME

A

FOUR

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16
Q

NUMBER OF AMINO ACIDS IN ALPHA GLOBIN CHAINS

A

141 AMINO ACIDS

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17
Q

NUMBER OF AMINO ACIDS IN BETA GLOBIN CHAINS

A

146 AMINO ACIDS

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18
Q

GLOBIN CHAINS CODED FOR BY CHROMOSOME 11

A

EPSILON
BETA
GAMMA

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19
Q

GLOBIN CHAINS CODED FOR BY CHROMOSOME 16

A

ALPHA
ZETA

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20
Q

EMBRYONIC HEMOGLOBIN

A

GOWER 1
GOWER 2
PORTLAND

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21
Q

FETAL HEMOGLOBIN

A

Hgb F (Predominant)
Hgb A1 (Detectable)

22
Q

ADULT HEMOGLOBIN

A

Hgb F
Hgb A (Predominant)
Hgb A2

23
Q

GLOBIN CHAINS OF EMBRYONIC HEMOGLOBIN

A

GOWER 1 — 2 ZETA, 2 EPSILON
GOWER 2 — 2 ALPHA, 2 EPSILON
PORTLAND — 2 ZETA, 2 GAMMA

24
Q

GLOBIN CHAINS OF FETAL HEMOGLOBIN

A

2 ALPHA
2 GAMMA

25
Q

GLOBIN CHAINS OF ADULT HEMOGLOBIN

A

HGB A — 2 ALPHA, 2 BETA
HGB A2 — 2 ALPHA, 2 DELTA

26
Q

[DYSHEMOOGLOBIN]
FORMED BY REVERSIBLE OXIDATION OF HEME IRON TO THE FERRIC STATE (Fe3+)

A

METHEMOGLOBIN

27
Q

IRON STATE THAT CANNOT TRANSPORT O2

A

FERRIC STATE (Fe3+)

28
Q

IRON STATE THAT CAN TRANSPORT O2

A

FERROUS (Fe2+)

29
Q

[DYSHEMOGLOBIN]
CAUSES INCREASED LEVELS OF CYANOSIS AND SYMPTOMS OF HYPOXIA

A

METHEMOGLOBIN

30
Q

OTHER TERM FOR METHEMOGLOBIN

A

HEMIGLOBIN

31
Q

[DYSHEMOGLOBIN]
FORMED BY THE IRREVERSIBLE OXIDATION OF HEMOGLOBIN

A

SULFHEMOGLOBIN

32
Q

CAUSES OF SULFHEMOGLOBIN

A

DRUGS (Sulfonamides, phenacetin, nitrites, phenylhydrazine)

EXPOSURE TO SULFUR CHEMICALS

33
Q

[TRUE OR FALSE]
BECAUSE SULFHEMOGLOBIN CAUSES CYANOSIS, IT CAN BE MEASURED BY THE CYANMETHEMOGLOBIN METHOD

A

FALSE

34
Q

[DYSHEMOGLOBIN]
GREENISH PIGMENT

A

SULFHEMOGLOBIN

35
Q

[DYSHEMOGLOBIN]
FORMED BY THE ADDITION OF A SULFUR ATOM TO THE PYRROLE RING OF HEME

A

SULFHEMOGLOBIN

36
Q

[DYSHEMOGLOBIN]
FORMED BY THE COMBINATION OF CARBON MONOXIDE WITH HEME IRON

A

CARBOXYHEMOGLOBIN

37
Q

[DYSHEMOGLOBIN]
AFFINITY OF CARBON MONOXIDE FOR HEMOGLOBIN IS 240X MORE THAN O2

A

CARBOXYHEMOGLOBIN

38
Q

WAVELENGTH AT WHICH CARBOXYHEMOGLOBIN IS DETECTED

A

540 NM

39
Q

[DYSHEMOGLOBIN]
SCARLET RED

A

OXYHEMOGLOBIN

40
Q

[DYSHEMOGLOBIN]
DARK RED

A

DEOXYHEMOGLOBIN

41
Q

[DYSHEMOGLOBIN]
CHERRY RED

A

CARBOXYHEMOGLOBIN

42
Q

[DYSHEMOGLOBIN]
REDUCED HEMOGLOBIN

A

DEOXYHEMOGLOBIN

43
Q

[DYSHEMOGLOBIN]
CHOCOLATE BROWN

A

METHEMOGLOBIN

44
Q

[DYSHEMOGLOBIN]
OXIDIZED HEMOGLOBIN

A

METHEMOGLOBIN

45
Q

[DYSHEMOGLOBIN]
15% OF TOTAL HEMOGLOBIN

A

METHEMOGLOBIN

46
Q

SUBSTANCE USED TO TREAT CYANOSIS

A

METHYLENE BLUE

47
Q

[DYSHEMOGLOBIN]
MEASURED AT 540 NM

A

CARBOXYHEMOGLOBIN

48
Q

[DYSHEMOGLOBIN]
MEASURED AT 630 NM

A

METHEMOGLOBIN

49
Q

[DYSHEMOGLOBIN]
FORMED BY THE BINDING OF FERRICYANIDE WITH FERROUS IRON IN THE PRESENCE OF POTASSIUM CYANIDE

A

CYANMETHEMOGLOBIN

50
Q

[DYSHEMOGLOBIN]
MAUVE-LAVENDER

A

SULFHEMOGLOBIN

51
Q

FERRICYANIDE BINDS WITH FERROUS IRON IN THE PRESENCE OF WHAT CHEMICAL

A

POTASSIUM CYANIDE

52
Q

[DYSHEMOGLOBIN]
FORMED BY THE COMBINATION OF INORGANIC SULFIDES AND HEMOGLOBIN

A

SULFHEMOGLOBIN

HEMATOLOGY (13 decks)

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