LEC 6 - Food-borne Nematodes Pt. 1 Flashcards
Parasite/s found in Crabs, shrimp
Gnathostoma
Parasite/s found in Freshwater Fish
Capillaria
Parasite/s found in Marine fish
Anisakis, Gnathostoma, Pseudoterranova
Parasite/s found in Fruits, vegetables
Angiostrongylus, Ascaris
Parasite/s found in Squid
Anisakis
Parasite/s found in Water
Ascaris, Gnathostoma
Parasite/s found in Other Meat
Gnathostoma (frogs, snakes)
Trichinella (bear, cougar , horse, walrus, wild boar)
humans can get the disease from animal exposure (usually through ingestion – inadequate cooking/improper preparation)
ZOONOTIC PARASITES
Meat-borne parasites occurring in livestock (domesticated animals)
Farm to Fork Food Chain
Trichinella (infective encysted larvae is found in pork muscle) is example of what food chain
Farm to Fork Food Chain
Meat-borne parasites occurring in wildlife (bears, cougars, etc.)
Forest to Fork Food Chain
Example of Forest to Fork Food Chain
Trichinella
Fish-borne parasites –consumption of either
freshwater/seawater (aquatic/marine) fishes
Freshwater/Ocean/Pond to Fork Food Chain
Example of Freshwater/Ocean/Pond to
Fork Food Chain
Anisakis – usually from seawater and brackish water
Capillaria – ingestion of freshwater fish
- A metastrongyloid parasite (that occurs in the lungs of mammals)
Angiostrongylus
Rat Lungworm
Angiostrongylus/Parastrongylus cantonensis
Disease caused by A. cantonensis
Angiostrongyliasis, Eosinophilic meningitis/ Neural angiostrongyliasis
target is CNS occasionally, ocular disease
Angiostrongyliasis, Eosinophilic meningitis/ Neural angiostrongyliasis
Disease caused by A. costaricensis
Angiostrongyliasis, Eosinophilic gastroenteritis (abdominal/intestinal angiostrongyliasis)
Definitive host A. cantonencis
- Black/ House/ Roof/ Ship rat (Rattus rattus)
- Brown/Norway rat (Rattus norvegicus)
- Hispid cotton rat (Sigmodon hispidus)
Definitive host A. costaricensis
- Hispid cotton rat (Sigmodon hispidus) – Main
- Black rat (Rattus rattus)
- Pygmy rice rat (Oligoryzomys fulvescens)
- Short-tailed canemouse/ short-tailed zygodonts (Zygodontomys brevicauda)
- Spiny pocket mice (Heteromys adsperus)
Intermediate host of A. cantonensis
Gastropod (slugs and snails):
- Achatina spp.
- Biomphalaria spp.
- Bulinus spp.
- Lymnaea spp.
- Pomaecea spp.
In the Philippines:
* Achatina fulica (Giant African snail)
* Helicostyla macrostoma
* Hemiplecta sagittifera
* Vaginilus plebeius
*Veronicella altae
Intermediate host of A. costaricensis
Gastropod (slug):
- Limacidae family
- Veronicellidae family
Aberrant/ Incidental host of A. cantonensis
Humans, birds, wild and domestic mammals
Aberrant/ Incidental host of A. costaricensis
Humans, non-human primates, and other mammals (opossum, raccoons)
Distribution of A. cantonensis
Predominant in SEA, tropical Pacific Islands; seen also in Africa, Australia, Caribbean, Hawaii and Southern US
Distribution of A. costaricensis
Caribbean, Latin America
Specimen for A. cantonensis
Brain tissue, CSF (Neural)
Specimen for A. costaricensis
Intestinal tissue section
Laboratory Diagnosis of A. cantonensis
Abnormal CSF:
* Elevated pressure
* (+) protein
* (+) leukocyte
* Eosinophilia
* Rarely: (+) parasite larvae
Presence of proteins and leukocyte are signs of non-specific inflammatory reactions
Laboratory Diagnosis of A. costaricensis
Finding of eggs, larvae, or adult in tissue sections taken through biopsy/surgery
Molecular diagnosis of A. cantonensis
CSF real-time PCR –identification of parasite genes in a sample
Molecular diagnosis of A. costaricensis
Tissue conventional PCR, then DNA sequence analysis (no specific molecular test is available)
Treatment for A. cantonensis
None (Supportive treatment only)
Treatment for A. costaricensis
None, but may require surgery
Prevention and Control for A. cantonensis
- Health education
- Avoid consumption of raw/undercooked slugs, snails, freshwater shrimps, land crabs, frogs, monitor lizards (transport hosts), or contaminated vegetable and vegetable juices
- Remove slugs, snails, and rats near gardens and houses
- Thoroughly wash vegetables if eaten raw
Prevention and Control for A. costaricensis
- Health education
- Avoid consumption of raw/undercooked slugs or contaminated vegetable/vegetable juices
- Remove slugs and rats near gardens and houses
- Throughly wash hands and utensils after preparing slugs
- Thoroughly wash vegetables if eaten raw
Cantonensis: first found in
Canton, China
Costaricensis: first found in
Costa Rica
group of parasites that reside in lungs of certain mammals
Metastrongyloid
: reside in lungs of rodents
Angiostrongylus