Lec 4-2 Flashcards
Mitosis is
Cell reproduction
1 Haploid—> 2 Haploid cells
or
1 diploid–> 2 diploid
1 cell division
Meiosis is
Production of gametes for sexual reproduction
2 cell divisions
1 diploid –> 4 haploid cells
Sexual reproduction has 2 steps
Meiosis and fertilization
Fertilization
Merger of sperm and egg that produces a diploid organism
Meiosis 1 is
Reduction division
Reduces number of chromosomes
Meiosis 2 is
Equational division
No reduction in chromosome n
similar to mitosis
Prophase 1
event similar to mitosis
Chromosomes condense
Mitotic spindle forms
Nuclear envelope breaks down
Prophase 1
Events unlike mitosis
Homologous chromosomes pair up and physically associate (are not independent)
Leads to crossing over (key to genetic diversity)
Leptotene
Prophase 1
Chromosomes condense using condensin
Process occurs continuously
Zygotene
Prophase 1
When synapsis starts (close pairing of homologous chromosomes)
Bivalent or tetrad
Four chromatids undergoing synapsis
Synaptonemal complex
prophase 1
Protein structure that scaffolds interacting chromatids (thought to facilitate crossing over)
Crossing over
Segments from one sister chromatid “cross over” the other sister chromatid at points called chiasmata
Creates genetic variation
Rest of meiosis 1
Metaphase 1
Similar to mitosis
Align at the metaphase plate
However, homologous pairs are physically associated, so align together, not as single chromosomes in Mitosis
Interkinesis stage
Nuclear membrane reforms around chromosomes
Spindle breaks down
Chromosomes relax