Lec 4-1

Question 1

Spindle movement and kinetochores

Answer 1

Microtubules lengthen and shorten at both ends in order to move

Kinetochore recognizes the centromere of the chromosome and allow for attachment of microtubules

Question 2

Specific chromatid

Pole arrangement

Answer 2

Each centromere only connects to one sister chromatid

Thus all microtubule attachments to a chromatid are connected to one pole

Question 3

Metaphase

Answer 3

Chromosomes align along the metaphase plate

Connected to spindle poles and ready to be split apart

Question 4

Spindle assembly checkpoint

Answer 4

Critical quality control checkpoint

Question 5

Anaphase

Answer 5

Connections between sister chromatid break down and they pull apart into daughter chromosomes

Microtubules dissembled on both ends by molecular motor proteins, pull daughter chromosome to pole