lec 3: permeation Flashcards
1
Q
WHAT ARE BARRIERS TO DRUG MOVEMENT
A
2
Q
WHAT ARE CHARACTERISTICS OF BIO MEMBRANES
A
3
Q
WHAT IS POW
A
4
Q
EPITHELEAL CELLS QUALITIES? SO DRUGS MUST…..
A
5
Q
BBB QUALITY? SO DRUGS MUST…
A
6
Q
WHERE IN THE BBB ARE PERMEABLE TO DRUGS
A
7
Q
WHY IS BBB AN ISSUE IN DRUG TARGETING
A
8
Q
WHAT HAPPENS AT THE PALCENTA WRT DRUGS/ WHAT CAN CROSS? WHAT DETERMINES CROSSING?
A
9
Q
WHAT ARE TRANSPORTERS RESPONSIBLE FOR?
A
10
Q
CONTRAST PASSIVE VS FACILITATED DIFFUSION
A
11
Q
CONTRAST PRIMARY ACTIVE TRANSPORT VS SECONDARY ACTIVE TRANSPORT
A
12
Q
WHERE ARE COMMON SITES OF DRUG TRANSPORT
A
13
Q
DESCRIBE POLARIZATION OF ENTEROCYTES VS RENAL CELLS VS HEPATOCYTES VS BBB
A
14
Q
WHAT ARE SOLUTE CARRIER TRANSPORTERS? LOCALIZATION? WHAT ARE THE TYPES
A
15
Q
WHAT FAMILY ARE OATS IN/ HOW MANY? WHAT TYPE? SUBSTRATES? DRUGS THAT USE THEM?
A
